Selwyn S. Jayakar, Ph.D.
Institution:
The University of ToledoArea:
nicotinic receptors, neuropeptidesGoogle:
"Selwyn Jayakar"Mean distance: 17.37 (cluster 16)
Parents
Sign in to add mentor| Joseph F. Margiotta | grad student | 2009 | The University of Toledo | |
| (Abl family kinases regulate neuronal nicotinic receptors and synapses in chick ciliary ganglion neurons.) | ||||
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Publications
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| McGrath M, Hoyt H, Pence A, et al. (2020) Competitive Antagonism of Etomidate Action by Diazepam: In Vitro GABAA Receptor and In Vivo Zebrafish Studies. Anesthesiology |
| Jayakar SS, Chiara DC, Zhou X, et al. (2020) Photoaffinity labeling identifies an intersubunit steroid-binding site in heteromeric GABA type A (GABA) receptors. The Journal of Biological Chemistry |
| Wu B, Jayakar SS, Zhou X, et al. (2018) Inhibitable photolabeling by neurosteroid diazirine analog in the β3-Subunit of human hetereopentameric type A GABA receptors. European Journal of Medicinal Chemistry. 162: 810-824 |
| McGrath M, Yu Z, Jayakar SS, et al. (2018) Etomidate and Etomidate Analog Binding and Positive Modulation of γ-Aminobutyric Acid Type A Receptors: Evidence for a State-dependent Cutoff Effect. Anesthesiology |
| Ma C, Pejo E, McGrath M, et al. (2017) Competitive Antagonism of Anesthetic Action at the γ-Aminobutyric Acid Type A Receptor by a Novel Etomidate Analog with Low Intrinsic Efficacy. Anesthesiology |
| Jayakar SS, Ang G, Chiara DC, et al. (2017) Photoaffinity Labeling of Pentameric Ligand-Gated Ion Channels: A Proteomic Approach to Identify Allosteric Modulator Binding Sites. Methods in Molecular Biology (Clifton, N.J.). 1598: 157-197 |
| Jayakar SS, Zhou X, Savechenkov PY, et al. (2016) Identifying GABA-A Receptor Modulators that Bind to Intersubunit Sites in the GABA-A Receptor Transmembrane Domain Biophysical Journal. 110: 454a-455a |
| Mohamed TS, Jayakar SS, Hamouda AK. (2015) Orthosteric and Allosteric Ligands of Nicotinic Acetylcholine Receptors for Smoking Cessation. Frontiers in Molecular Neuroscience. 8: 71 |
| Jayakar SS, Zhou X, Savechenkov PY, et al. (2015) Positive and Negative Allosteric Modulation of an α1β3γ2 γ-Aminobutyric acid Type A (GABAA) Receptor by Binding to a Site in the Transmembrane Domain at the γ+-β- Interface. The Journal of Biological Chemistry |
| Jayakar SS, Pugh PC, Dale Z, et al. (2014) PACAP induces plasticity at autonomic synapses by nAChR-dependent NOS1 activation and AKAP-mediated PKA targeting. Molecular and Cellular Neurosciences. 63: 1-12 |