Patrick J. Gannon, Ph.D.

Affiliations: 
Pharmacology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular mechanisms underlying neuronal loss in neurodegenerative disorders
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Parents

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Kelly L. Jordan-Sciutto grad student 2014 Penn
 (Assessing the contribution of antiretroviral therapy to neuronal damage and death as a mediator of cognitive decline in HIV-associated neurocognitive disorders.)
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Publications

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Bond S, Lopez-Lloreda C, Gannon PJ, et al. (2020) The Integrated Stress Response and Phosphorylated Eukaryotic Initiation Factor 2α in Neurodegeneration. Journal of Neuropathology and Experimental Neurology
Stern AL, Ghura S, Gannon PJ, et al. (2018) BACE1 mediates HIV-associated and excitotoxic neuronal damage through an APP-dependent mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Gannon PJ, Akay-Espinoza C, Yee AC, et al. (2017) HIV Protease Inhibitors Alter Amyloid Precursor Protein Processing via β-Site Amyloid Precursor Protein Cleaving Enzyme-1 Translational Up-Regulation. The American Journal of Pathology. 187: 91-109
Jensen BK, Monnerie H, Mannell MV, et al. (2015) Altered Oligodendrocyte Maturation and Myelin Maintenance: The Role of Antiretrovirals in HIV-Associated Neurocognitive Disorders. Journal of Neuropathology and Experimental Neurology. 74: 1093-118
Akay C, Cooper M, Odeleye A, et al. (2014) Antiretroviral drugs induce oxidative stress and neuronal damage in the central nervous system. Journal of Neurovirology. 20: 39-53
Gannon P, Khan MZ, Kolson DL. (2011) Current understanding of HIV-associated neurocognitive disorders pathogenesis. Current Opinion in Neurology. 24: 275-83
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