Ithiel J. Frame, Ph.D.

Affiliations: 
Yeshiva University, New York, NY, United States 
Area:
NEUROTRANSMITTER-GATED ION CHANNELS, MALARIA PARASITE PHYSIOLOGY AND MECHANISMS OF CHLOROQUINE RESISTANCE
Google:
"Ithiel Frame"
Mean distance: 16.38 (cluster 16)
 
SNBCP

Parents

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Myles H. Akabas grad student 2013 Yeshiva University
 (Malaria parasite purine transporters: Function determination & inhibitor identification.)
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Publications

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Deniskin R, Frame IJ, Sosa Y, et al. (2016) Targeting the Plasmodium vivax equilibrative nucleoside transporter 1 (PvENT1) for antimalarial drug development. International Journal For Parasitology. Drugs and Drug Resistance. 6: 1-11
Frame IJ, Deniskin R, Rinderspacher A, et al. (2015) Yeast-based high-throughput screen identifies Plasmodium falciparum equilibrative nucleoside transporter 1 inhibitors that kill malaria parasites. Acs Chemical Biology. 10: 775-83
Frame IJ, Deniskin R, Arora A, et al. (2015) Purine import into malaria parasites as a target for antimalarial drug development. Annals of the New York Academy of Sciences. 1342: 19-28
Brunner R, Ng CL, Aissaoui H, et al. (2013) UV-triggered affinity capture identifies interactions between the Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) and antimalarial agents in live parasitized cells. The Journal of Biological Chemistry. 288: 22576-83
Frame IJ, Merino EF, Schramm VL, et al. (2012) Malaria parasite type 4 equilibrative nucleoside transporters (ENT4) are purine transporters with distinct substrate specificity. The Biochemical Journal. 446: 179-90
Riegelhaupt PM, Frame IJ, Akabas MH. (2010) Transmembrane segment 11 appears to line the purine permeation pathway of the Plasmodium falciparum equilibrative nucleoside transporter 1 (PfENT1). The Journal of Biological Chemistry. 285: 17001-10
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