Christopher C. Mader, Ph.D.

Affiliations: 
Yale University, New Haven, CT 
Area:
Neuronal morphogenesis and degeneration; stress; schizophrenia; cell migration; cancer; metastasis; adhesion receptors
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"Christopher Mader"
Mean distance: 17.17 (cluster 32)
 
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Parents

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Anthony J. Koleske grad student 2011 Yale
 (Regulation of Cellular Protrusions by Abl-family Kinase-mediated Cortactin Phosphorylation.)
Chad A. Mirkin post-doc 2011-2011 Northwestern (Chemistry Tree)
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Publications

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Larpenteur K, Waal Ld, Wang L, et al. (2019) Abstract C022: Large scale phenotypic screening using PRISM, integrated with functional genomic screening and transcriptional profiling accelerates target identification of cytotoxic small molecules Molecular Cancer Therapeutics. 18
Boudreau A, Roth J, Rong J, et al. (2019) Abstract B121: An oncogene-linked prodrug strategy in lung cancer Molecular Cancer Therapeutics. 18
Rosenberg BJ, Gil-Henn H, Mader CC, et al. (2017) Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells. Molecular Biology of the Cell
Sheffer M, Wieten L, Yu C, et al. (2017) Identification and Validation of Molecular Markers of Tumor Cell Resistance to Natural Killer Cells through CRISPR-Based Screens and Large-Scale Phenotypic Screens of Pooled Tumor Cell Lines Blood. 130: 623-623
Radovic-Moreno AF, Chernyak N, Mader CC, et al. (2015) Immunomodulatory spherical nucleic acids. Proceedings of the National Academy of Sciences of the United States of America. 112: 3892-7
Gifford SM, Liu W, Mader CC, et al. (2014) Two amino acid residues confer different binding affinities of Abelson family kinase SRC homology 2 domains for phosphorylated cortactin. The Journal of Biological Chemistry. 289: 19704-13
Giam LR, Massich MD, Hao L, et al. (2012) Scanning probe-enabled nanocombinatorics define the relationship between fibronectin feature size and stem cell fate. Proceedings of the National Academy of Sciences of the United States of America. 109: 4377-82
Magalhaes MA, Larson DR, Mader CC, et al. (2011) Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway. The Journal of Cell Biology. 195: 903-20
Hornick JE, Mader CC, Tribble EK, et al. (2011) Amphiastral mitotic spindle assembly in vertebrate cells lacking centrosomes. Current Biology : Cb. 21: 598-605
Chung C, Mader CC, Schmitz JC, et al. (2011) The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer. Laboratory Investigation; a Journal of Technical Methods and Pathology. 91: 732-43
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