William R. Thelin, Ph.D.
Affiliations: | University of North Carolina, Chapel Hill, Chapel Hill, NC |
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"William Thelin"Mean distance: 18.01 (cluster 11) | S | N | B | C | P |
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Sign in to add mentor| Sharon Milgram | grad student | 2006 | UNC Chapel Hill | |
| (The regulation of CFTR by protein -protein interactions.) | ||||
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| Zachos NC, Hodson C, Kovbasnjuk O, et al. (2008) Elevated intracellular calcium stimulates NHE3 activity by an IKEPP (NHERF4) dependent mechanism. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 22: 693-704 |
| Hirsh AJ, Zhang J, Zamurs A, et al. (2008) Pharmacological properties of N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-4-[4-(2,3-dihydroxypropoxy)phenyl]butyl-guanidine methanesulfonate (552-02), a novel epithelial sodium channel blocker with potential clinical efficacy for cystic fibrosis lung disease. The Journal of Pharmacology and Experimental Therapeutics. 325: 77-88 |
| Thelin WR, Boucher RC. (2007) The epithelium as a target for therapy in cystic fibrosis. Current Opinion in Pharmacology. 7: 290-5 |
| Thelin WR, Chen Y, Gentzsch M, et al. (2007) Direct interaction with filamins modulates the stability and plasma membrane expression of CFTR. The Journal of Clinical Investigation. 117: 364-74 |
| Chen Y, Thelin WR, Yang B, et al. (2006) Transient anchorage of cross-linked glycosyl-phosphatidylinositol-anchored proteins depends on cholesterol, Src family kinases, caveolin, and phosphoinositides. The Journal of Cell Biology. 175: 169-78 |
| Thelin WR, Kesimer M, Tarran R, et al. (2005) The cystic fibrosis transmembrane conductance regulator is regulated by a direct interaction with the protein phosphatase 2A. The Journal of Biological Chemistry. 280: 41512-20 |
| Thelin WR, Hodson CA, Milgram SL. (2005) Beyond the brush border: NHERF4 blazes new NHERF turf. The Journal of Physiology. 567: 13-9 |
| Loiselle DR, Thelin WR, Parker CE, et al. (2005) Improved protein identification through the use of unstained gels. Journal of Proteome Research. 4: 992-7 |
| Hegedüs T, Sessler T, Scott R, et al. (2003) C-terminal phosphorylation of MRP2 modulates its interaction with PDZ proteins. Biochemical and Biophysical Research Communications. 302: 454-61 |
| Scott RO, Thelin WR, Milgram SL. (2002) A novel PDZ protein regulates the activity of guanylyl cyclase C, the heat-stable enterotoxin receptor. The Journal of Biological Chemistry. 277: 22934-41 |