Brian T. Hawkins

Affiliations: 
NIH/NIEHS, Durham, NC, United States 
Area:
blood-brain barrier, drug delivery
Website:
http://brianthawkins.googlepages.com
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"Brian Hawkins"
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Parents

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Thomas P. Davis grad student 1999-2004 University of Arizona
 (Nicotinic modulation of cerebral microvascular permeability.)
David S. Miller post-doc 2006- NIH/NIEHS
Richard D. Egleton post-doc 2004-2006 University of Arizona
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Publications

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Koo Y, Hawkins BT, Yun Y. (2018) Three-dimensional (3D) tetra-culture brain on chip platform for organophosphate toxicity screening. Scientific Reports. 8: 2841
Izawa Y, Gu YH, Osada T, et al. (2017) β1-integrin-matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17722108
Sellgren KL, Hawkins BT, Grego S. (2015) An optically transparent membrane supports shear stress studies in a three-dimensional microfluidic neurovascular unit model. Biomicrofluidics. 9: 061102
Hawkins BT, Grego S, Sellgren KL. (2015) Three-dimensional culture conditions differentially affect astrocyte modulation of brain endothelial barrier function in response to transforming growth factor β1. Brain Research. 1608: 167-76
Hawkins BT, Gu YH, Izawa Y, et al. (2015) Dabigatran abrogates brain endothelial cell permeability in response to thrombin. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 985-92
Hawkins BT. (2015) Hitting a moving target: Therapeutic delivery in the injured brain Advances in Non-Invasive Drug Delivery to the Brain. 22-31
del Zoppo GJ, Izawa Y, Hawkins BT. (2013) Hemostasis and alterations of the central nervous system. Seminars in Thrombosis and Hemostasis. 39: 856-75
Hawkins BT, Gu YH, Izawa Y, et al. (2013) Disruption of dystroglycan-laminin interactions modulates water uptake by astrocytes. Brain Research. 1503: 89-96
Cannon RE, Peart JC, Hawkins BT, et al. (2012) Targeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brain. Proceedings of the National Academy of Sciences of the United States of America. 109: 15930-5
Miller DS, Hawkins BT. (2012) Blood-Brain Barrier: Considerations in Drug Development and Delivery Chemical Biology: Approaches to Drug Discovery and Development to Targeting Disease. 133-146
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