Chen Yao, Ph.D.
Affiliations: | Pathology | Case Western Reserve University, Cleveland Heights, OH, United States |
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Parents
Sign in to add mentor| Shu G. Chen | grad student | 2012 | Case Western | |
| (Modeling LRRK2-associated Parkinson's disease in C. elegans.) | ||||
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Publications
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| Schaffner A, Li X, Gomez-Llorente Y, et al. (2019) Vitamin B modulates Parkinson's disease LRRK2 kinase activity through allosteric regulation and confers neuroprotection. Cell Research |
| Johnson WM, Golczak M, Choe K, et al. (2016) Regulation of DJ-1 by glutaredoxin 1 in vivo - implications for Parkinson's disease. Biochemistry |
| Johnson WM, Yao C, Siedlak SL, et al. (2015) Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease. Human Molecular Genetics. 24: 1322-35 |
| Yao C, Johnson WM, Gao Y, et al. (2013) Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity. Human Molecular Genetics. 22: 328-44 |
| Yao C, El Khoury R, Wang W, et al. (2010) LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease. Neurobiology of Disease. 40: 73-81 |