Mahalakshmi Shankaran, Ph.D.

Affiliations: 
University of Cincinnati, Cincinnati, OH 
Area:
Neuropharmacology of amphetamines
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"Mahalakshmi Shankaran"
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Gary Gudelsky grad student 2000 University of Cincinnati
 (Consequences and mechanism of 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity.)
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Publications

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Shankaran M, Shearer TW, Stimpson SA, et al. (2015) Proteome-wide muscle protein fractional synthesis rates predict muscle mass gain in response to a selective androgen receptor modulator in rats. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00257.2015
Chen Z, Tetzlaff J, Sripathirathan K, et al. (2005) Paroxetine is effective in desensitizing 5-HT1A receptor function in adult offspring exposed prenatally to cocaine. Psychopharmacology. 180: 316-26
Damjanoska KJ, Muma NA, Zhang Y, et al. (2003) Neuroendocrine evidence that (S)-2-(chloro-5-fluoro-indol- l-yl)-1-methylethylamine fumarate (Ro 60-0175) is not a selective 5-hydroxytryptamine(2C) receptor agonist. The Journal of Pharmacology and Experimental Therapeutics. 304: 1209-16
Darvesh AS, Shankaran M, Gudelsky GA. (2002) 3,4-Methylenedioxymethamphetamine produces glycogenolysis and increases the extracellular concentration of glucose in the rat brain. The Journal of Pharmacology and Experimental Therapeutics. 301: 138-44
Shankaran M, Yamamoto BK, Gudelsky GA. (2001) Ascorbic acid prevents 3,4-methylenedioxymethamphetamine (MDMA)-induced hydroxyl radical formation and the behavioral and neurochemical consequences of the depletion of brain 5-HT. Synapse (New York, N.Y.). 40: 55-64
Shankaran M, Yamamoto BK, Gudelsky GA. (1999) Involvement of the serotonin transporter in the formation of hydroxyl radicals induced by 3,4-methylenedioxymethamphetamine. European Journal of Pharmacology. 385: 103-10
Shankaran M, Gudelsky GA. (1999) A neurotoxic regimen of MDMA suppresses behavioral, thermal and neurochemical responses to subsequent MDMA administration. Psychopharmacology. 147: 66-72
Shankaran M, Yamamoto BK, Gudelsky GA. (1999) Mazindol attenuates the 3,4-methylenedioxymethamphetamine-induced formation of hydroxyl radicals and long-term depletion of serotonin in the striatum. Journal of Neurochemistry. 72: 2516-22
Shankaran M, Gudelsky GA. (1998) Effect of 3,4-methylenedioxymethamphetamine (MDMA) on hippocampal dopamine and serotonin. Pharmacology, Biochemistry, and Behavior. 61: 361-6
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