Jennifer J. O'Brien, Ph.D.

Excitation-contraction coupling

Kurt G. Beam	grad student	2002	Colorado State
(Structure-function relationships of the ryanodine receptor.)

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Hurne AM, O'Brien JJ, Wingrove D, et al. (2005) Ryanodine receptor type 1 (RyR1) mutations C4958S and C4961S reveal excitation-coupled calcium entry (ECCE) is independent of sarcoplasmic reticulum store depletion. The Journal of Biological Chemistry. 280: 36994-7004
O'Brien JJ, Feng W, Allen PD, et al. (2002) Ca2+ activation of RyR1 is not necessary for the initiation of skeletal-type excitation-contraction coupling. Biophysical Journal. 82: 2428-35
Proenza C, O'Brien J, Nakai J, et al. (2002) Identification of a region of RyR1 that participates in allosteric coupling with the alpha(1S) (Ca(V)1.1) II-III loop. The Journal of Biological Chemistry. 277: 6530-5
Avila G, O'Brien JJ, Dirksen RT. (2001) Excitation--contraction uncoupling by a human central core disease mutation in the ryanodine receptor. Proceedings of the National Academy of Sciences of the United States of America. 98: 4215-20