Matthew D. Howell, Ph.D.
Affiliations: | Interdisciplinary Toxicology | University of Arkansas for Medical Sciences, United States |
Area:
neural plasticity, matrix metalloproteinasesGoogle:
"Matthew Howell"Mean distance: 33747.2
Parents
Sign in to add mentor| Paul E. Gottschall | grad student | 2012 | UAMS | |
| (Extracellular proteoglycans and their cleaving metalloproteinases are associated with neural plasticity.) | ||||
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Publications
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| Howell MD, Ottesen EW, Singh NN, et al. (2017) TIA1 is a gender-specific disease modifier of a mild mouse model of spinal muscular atrophy. Scientific Reports. 7: 7183 |
| Singh NN, Howell MD, Androphy EJ, et al. (2017) How the discovery of ISS-N1 led to the first medical therapy for spinal muscular atrophy. Gene Therapy |
| Howell MD, Ottesen EW, Singh NN, et al. (2017) Gender-Specific Amelioration of SMA Phenotype upon Disruption of a Deep Intronic Structure by an Oligonucleotide. Molecular Therapy : the Journal of the American Society of Gene Therapy |
| Singh RN, Howell MD, Ottesen EW, et al. (2017) Diverse role of Survival Motor Neuron Protein. Biochimica Et Biophysica Acta |
| Ottesen EW, Howell MD, Singh NN, et al. (2016) Severe impairment of male reproductive organ development in a low SMN expressing mouse model of spinal muscular atrophy. Scientific Reports. 6: 20193 |
| Howell MD, Bailey LA, Cozart MA, et al. (2015) Hippocampal administration of chondroitinase ABC increases plaque-adjacent synaptic marker and diminishes amyloid burden in aged APPswe/PS1dE9 mice. Acta Neuropathologica Communications. 3: 54 |
| Gottschall PE, Howell MD. (2015) ADAMTS expression and function in central nervous system injury and disorders. Matrix Biology : Journal of the International Society For Matrix Biology. 44: 70-76 |
| Howell MD, Singh NN, Singh RN. (2014) Advances in therapeutic development for spinal muscular atrophy. Future Medicinal Chemistry. 6: 1081-99 |
| Keil JM, Seo J, Howell MD, et al. (2014) A short antisense oligonucleotide ameliorates symptoms of severe mouse models of spinal muscular atrophy. Molecular Therapy. Nucleic Acids. 3: e174 |
| Sivanesan S, Howell MD, Didonato CJ, et al. (2013) Antisense oligonucleotide mediated therapy of spinal muscular atrophy. Translational Neuroscience. 4 |