Tiffany A. Heanue, Ph.D.

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
genetics, morphogenesis, limb, evolution
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"Tiffany Heanue"

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Clifford J. Tabin grad student 2000 Harvard
 (Vertebrate dachshund genes function in evolutionarily conserved regulatory cassettes to control developmental fate.)
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Publications

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Jiang Q, Arnold S, Heanue T, et al. (2015) Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability. American Journal of Human Genetics. 96: 581-96
Knight RD, Mebus K, d'Angelo A, et al. (2011) Ret signalling integrates a craniofacial muscle module during development. Development (Cambridge, England). 138: 2015-24
Heanue TA, Pachnis V. (2011) Prospective identification and isolation of enteric nervous system progenitors using Sox2. Stem Cells (Dayton, Ohio). 29: 128-40
Heanue TA, Pachnis V. (2008) Ret isoform function and marker gene expression in the enteric nervous system is conserved across diverse vertebrate species. Mechanisms of Development. 125: 687-99
Heanue TA, Pachnis V. (2006) Expression profiling the developing mammalian enteric nervous system identifies marker and candidate Hirschsprung disease genes. Proceedings of the National Academy of Sciences of the United States of America. 103: 6919-24
Kardon G, Heanue TA, Tabin CJ. (2002) Pax3 and Dach2 positive regulation in the developing somite. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 224: 350-5
Inoue Y, Mito T, Miyawaki K, et al. (2002) Correlation of expression patterns of homothorax, dachshund, and Distal-less with the proximodistal segmentation of the cricket leg bud. Mechanisms of Development. 113: 141-8
Heanue TA, Davis RJ, Rowitch DH, et al. (2002) Dach1, a vertebrate homologue of Drosophila dachshund, is expressed in the developing eye and ear of both chick and mouse and is regulated independently of Pax and Eya genes. Mechanisms of Development. 111: 75-87
Davis RJ, Shen W, Sandler YI, et al. (2001) Characterization of mouse Dach2, a homologue of Drosophila dachshund. Mechanisms of Development. 102: 169-79
Heanue TA, Reshef R, Davis RJ, et al. (1999) Synergistic regulation of vertebrate muscle development by Dach2, Eya2, and Six1, homologs of genes required for Drosophila eye formation. Genes & Development. 13: 3231-43
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