John R. Cirrito, Ph.D.

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
Alzheimer's, amyloid
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"John Cirrito"
Mean distance: 16.52 (cluster 31)
 

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David M. Holtzman grad student 2004 Washington University
 (Amyloid-beta metabolism in the brain interstitial fluid of a mouse model of Alzheimer's disease.)
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Publications

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Sapkota D, Florian C, Doherty BM, et al. (2022) Aqp4 stop codon readthrough facilitates amyloid-β clearance from the brain. Brain : a Journal of Neurology
Miller RL, Dhavale DD, O'Shea JY, et al. (2022) Quantifying regional α -synuclein, amyloid β, and tau accumulation in lewy body dementia. Annals of Clinical and Translational Neurology
Rosene MJ, Hsu S, Martinez R, et al. (2021) Defining the role of PLD3 in Alzheimer's disease pathology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 17: e058730
Izzo NJ, Yuede CM, LaBarbera KM, et al. (2021) Preclinical and clinical biomarker studies of CT1812: A novel approach to Alzheimer's disease modification. Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Yuede CM, Wallace CE, Davis TA, et al. (2020) Pimavanserin, a 5HT receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer's disease. Journal of Neurochemistry
George AA, Vieira JM, Xavier-Jackson C, et al. (2020) Implications of oligomeric amyloid-beta (oAβ42) signaling through α7β2-nicotinic acetylcholine receptors (nAChR) on basal forebrain cholinergic neuronal intrinsic excitability and cognitive decline. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Cirrito JR, Wallace CE, Yan P, et al. (2020) Effect of Escitalopram on Aβ levels and plaque load in an Alzheimer mouse model. Neurology
Sheline YI, Snider BJ, Beer JC, et al. (2020) Effect of escitalopram dose and treatment duration on CSF Aβ levels in healthy older adults: A controlled clinical trial. Neurology
Thomas R, Zimmerman SD, Yuede KM, et al. (2020) Exercise Training Results in Lower Amyloid Plaque Load and Greater Cognitive Function in an Intensity Dependent Manner in the Tg2576 Mouse Model of Alzheimer's Disease. Brain Sciences. 10
Holth JK, Fritschi SK, Wang C, et al. (2019) The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans. Science (New York, N.Y.)
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