Gabriel M. Simon, Ph.D.
Affiliations: | 2009 | Scripps Research Institute, La Jolla, La Jolla, CA, United States |
Area:
Medicinal ChemistryGoogle:
"Gabriel Simon"Mean distance: 18.87 | S | N | B | C | P |
Parents
Sign in to add mentor| Benjamin F. Cravatt | grad student | 2009 | Scripps Institute | |
| (Part I. Investigation of the molecular mechanisms responsible for anandamide biosynthesis. Part II. Development and application of proteomic methods to identify protease substrates.) | ||||
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Publications
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| Li H, Ma T, Remsberg JR, et al. (2023) Assigning functionality to cysteines by base editing of cancer dependency genes. Nature Chemical Biology |
| Lazear MR, Remsberg JR, Jaeger MG, et al. (2023) Proteomic discovery of chemical probes that perturb protein complexes in human cells. Molecular Cell |
| Kavanagh ME, Horning BD, Khattri R, et al. (2022) Author Correction: Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine. Nature Chemical Biology |
| Kavanagh ME, Horning BD, Khattri R, et al. (2022) Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine. Nature Chemical Biology |
| Zhang X, Luukkonen LM, Eissler CL, et al. (2021) DCAF11 Supports Targeted Protein Degradation by Electrophilic Proteolysis-Targeting Chimeras. Journal of the American Chemical Society |
| László ZI, Lele Z, Zöldi M, et al. (2020) ABHD4-dependent developmental anoikis safeguards the embryonic brain. Nature Communications. 11: 4363 |
| Vaisar T, Hu JH, Airhart N, et al. (2020) Parallel Murine and Human Plaque Proteomics Reveals Pathways of Plaque Rupture. Circulation Research |
| Vinogradova EV, Zhang X, Remillard D, et al. (2020) An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell |
| Chen AL, Lum KM, Lara-Gonzalez P, et al. (2019) Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan. Nature Chemical Biology |
| Clapper JR, Henry CL, Niphakis MJ, et al. (2018) Monoacylglycerol Lipase Inhibition in Human and Rodent Systems Supports Clinical Evaluation of Endocannabinoid Modulators. The Journal of Pharmacology and Experimental Therapeutics |