William A. Holtz, Ph.D.

2004

Karen O'Malley	grad student	2004	Washington University
(The role of oxidative stress and unfolded protein response in toxin-based models of Parkinson's disease.)

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Holtz WA, Turetzky JM, Jong YJ, et al. (2006) Oxidative stress-triggered unfolded protein response is upstream of intrinsic cell death evoked by parkinsonian mimetics. Journal of Neurochemistry. 99: 54-69
Holtz WA, Turetzky JM, O'Malley KL. (2005) Microarray expression profiling identifies early signaling transcripts associated with 6-OHDA-induced dopaminergic cell death. Antioxidants & Redox Signaling. 7: 639-48
O'Malley KL, Liu J, Lotharius J, et al. (2003) Targeted expression of BCL-2 attenuates MPP+ but not 6-OHDA induced cell death in dopaminergic neurons. Neurobiology of Disease. 14: 43-51
Holtz WA, O'Malley KL. (2003) Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons. The Journal of Biological Chemistry. 278: 19367-77