Nyamekye Obeng-Adjei, Ph.D.

Affiliations: 
2013 Pharmacology University of Pennsylvania, Philadelphia, PA, United States 
Area:
DNA vaccine, HIV
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Parents

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David B. Weiner grad student 2013 Penn
 (Investigating and manipulating immune responses to hepatotropic pathogens using synthetic DNA.)
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Publications

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Obeng-Adjei N, Portugal S, Holla P, et al. (2017) Malaria-induced interferon-γ drives the expansion of Tbethi atypical memory B cells. Plos Pathogens. 13: e1006576
Kurup SP, Obeng-Adjei N, Anthony SM, et al. (2017) Regulatory T cells impede acute and long-term immunity to blood-stage malaria through CTLA-4. Nature Medicine
Portugal S, Obeng-Adjei N, Moir S, et al. (2017) Atypical memory B cells in human chronic infectious diseases: An interim report. Cellular Immunology
Hansen DS, Obeng-Adjei N, Ly A, et al. (2016) Emerging concepts in T follicular helper cell responses to malaria. International Journal For Parasitology
Obeng-Adjei N, Portugal S, Tran TM, et al. (2015) Circulating Th1-Cell-type Tfh Cells that Exhibit Impaired B Cell Help Are Preferentially Activated during Acute Malaria in Children. Cell Reports
Zander RA, Obeng-Adjei N, Guthmiller JJ, et al. (2015) PD-1 Co-inhibitory and OX40 Co-stimulatory Crosstalk Regulates Helper T Cell Differentiation and Anti-Plasmodium Humoral Immunity. Cell Host & Microbe. 17: 628-41
Yan J, Chu JS, Obeng-Adjei N, et al. (2015) 417. Induction of Potent Cytotoxic and Antitumor Activity By a Highly Optimized hTERT DNA Vaccine Molecular Therapy. 23: S165
Villarreal DO, Wise MC, Walters JN, et al. (2014) Alarmin IL-33 acts as an immunoadjuvant to enhance antigen-specific tumor immunity. Cancer Research. 74: 1789-800
Yan J, Pankhong P, Shin TH, et al. (2013) Highly optimized DNA vaccine targeting human telomerase reverse transcriptase stimulates potent antitumor immunity. Cancer Immunology Research. 1: 179-89
Obeng-Adjei N, Hutnick NA, Yan J, et al. (2013) DNA vaccine cocktail expressing genotype A and C HBV surface and consensus core antigens generates robust cytotoxic and antibody responses in mice and Rhesus macaques. Cancer Gene Therapy. 20: 652-62
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