Shafinaz Akhter, Ph.D.

Affiliations: 
2002 Johns Hopkins University, Baltimore, MD 
Area:
IBD, Gastroenterology, Sodium hydrogen exchange
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"Shafinaz Akhter"
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Parents

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Mark Donowitz grad student 2002 Johns Hopkins
 (Membrane trafficking and regulation of the epithelial sodium(+)/proton exchanger isoform, NHE3.)
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Publications

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Akhter S, Kovbasnjuk O, Li X, et al. (2002) Na(+)/H(+) exchanger 3 is in large complexes in the center of the apical surface of proximal tubule-derived OK cells. American Journal of Physiology. Cell Physiology. 283: C927-40
Cavet ME, Akhter S, Murtazina R, et al. (2001) Half-lives of plasma membrane Na(+)/H(+) exchangers NHE1-3: plasma membrane NHE2 has a rapid rate of degradation. American Journal of Physiology. Cell Physiology. 281: C2039-48
Donowitz M, Janecki A, Akhter S, et al. (2000) Short-term regulation of NHE3 by EGF and protein kinase C but not protein kinase A involves vesicle trafficking in epithelial cells and fibroblasts. Annals of the New York Academy of Sciences. 915: 30-42
Janecki AJ, Janecki M, Akhter S, et al. (2000) Quantitation of plasma membrane expression of a fusion protein of Na/H exchanger NHE3 and green fluorescence protein (GFP) in living PS120 fibroblasts. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 48: 1479-92
Janecki AJ, Janecki M, Akhter S, et al. (2000) Basic fibroblast growth factor stimulates surface expression and activity of Na(+)/H(+) exchanger NHE3 via mechanism involving phosphatidylinositol 3-kinase. The Journal of Biological Chemistry. 275: 8133-42
Akhter S, Cavet ME, Tse CM, et al. (2000) C-terminal domains of Na(+)/H(+) exchanger isoform 3 are involved in the basal and serum-stimulated membrane trafficking of the exchanger. Biochemistry. 39: 1990-2000
Cavet ME, Akhter S, Tse C, et al. (2000) Differences in plasma membrane half-life and membrane trafficking of the epithelial Na+/H+exchangers NHE2 and NHE3: Insights into functions of these proteins Gastroenterology. 118: A597
Akhter S, Kovbasnjuk O, Hubbard A, et al. (2000) Separate functions for brush border membrane and endosomal NHE3 in a polarized epithelial cell line Gastroenterology. 118: A596
Cavet ME, Akhter S, de Medina FS, et al. (1999) Na/Hexchangers (NHE1-3) have similar turnover numbers but different percentages on the cell surface. American Journal of Physiology. Cell Physiology. 277: C1111-C1121
Akhter S, Nath SK, Tse CM, et al. (1999) Squalamine, a novel cationic steroid, specifically inhibits the brush-border Na/Hexchanger isoform NHE3. American Journal of Physiology. Cell Physiology. 276: C136-C144
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