Earl Gillespie, Ph.D.

Affiliations: 
2013 Boston University, Boston, MA, United States 
Area:
Neuroscience
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"Earl Gillespie"
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Susan E. Leeman grad student 2013 Boston University
 (Colonic epithelial genes in the transition from chronic inflammation to carcinoma in human colitis-associated cancer: Focus on the truncated neurokinin-1 receptor.)
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Publications

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Cassidy MR, Sheldon HK, Gainsbury ML, et al. (2014) The neurokinin 1 receptor regulates peritoneal fibrinolytic activity and postoperative adhesion formation. The Journal of Surgical Research. 191: 12-8
Brady M, Gillespie E, Zhang M, et al. (2014) Protease-Activated Receptors (PARs) 1 and 2 Are Upregulated in Ischemic Peritoneal Adhesion Tissue in a Rat Model of Adhesion Formation and in Hypoxic Human Mesothelial Cells In Vitro: Potential Molecular Targets for the Prevention of Intraabdominal Adhesions Journal of Surgical Research. 186: 679
Gillespie E, Leeman SE, Watts LA, et al. (2013) Plasminogen activator inhibitor-1 is increased in colonic epithelial cells from patients with colitis-associated cancer. Journal of Crohn's & Colitis. 7: 403-11
Bushell KN, Leeman SE, Gillespie E, et al. (2011) LITAF mediation of increased TNF-α secretion from inflamed colonic lamina propria macrophages. Plos One. 6: e25849
Gillespie E, Leeman SE, Watts LA, et al. (2011) Truncated neurokinin-1 receptor is increased in colonic epithelial cells from patients with colitis-associated cancer. Proceedings of the National Academy of Sciences of the United States of America. 108: 17420-5
Gillespie E, Hetzel JT, Coukos J, et al. (2010) M1951 Gene Expression of the Truncated Neurokinin-1 Receptor as Well as Two NF-kB Subunits is Altered in the Transition of Colonic Epithelial Cells From Quiescent Colitis to High Grade Dysplasia to Carcinoma in Colitis Associated Colorectal Cancer Gastroenterology. 138: S-446
Gainsbury ML, Abdou R, Chu DI, et al. (2010) Hypoxia causes upregulation of the Neurokinin-1 Receptor (NK-1R) in rat peritoneal mesothelial cells (RPMCs): A necessary event in intraabdominal adhesion formation Journal of the American College of Surgeons. 211: S14-S15
Chen CD, Podvin S, Gillespie E, et al. (2007) Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17. Proceedings of the National Academy of Sciences of the United States of America. 104: 19796-801
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