Stephen Tapscott

Affiliations: 
Human Biology Fred Hutchinson Cancer Research Center, Seattle, WA, United States 
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"Stephen Tapscott"
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Publications

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Wong CJ, Friedman SD, Snider L, et al. (2024) Regional and bilateral MRI and gene signatures in facioscapulohumeral dystrophy: implications for clinical trial design and mechanisms of disease progression. Human Molecular Genetics
Zheng D, Wondergem A, Kloet S, et al. (2023) snRNA-seq analysis in multinucleated myogenic FSHD cells identifies heterogeneous FSHD transcriptome signatures associated with embryonic-like program activation and oxidative stress-induced apoptosis. Human Molecular Genetics
Hamm DC, Paatela EM, Bennett SR, et al. (2023) The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs. Plos Biology. 21: e3002317
Smith AA, Nip Y, Bennett SR, et al. (2023) DUX4 expression in cancer induces a metastable early embryonic totipotent program. Cell Reports. 42: 113114
Šikrová D, Testa AM, Willemsen I, et al. (2023) SMCHD1 and LRIF1 converge at the FSHD-associated D4Z4 repeat and LRIF1 promoter yet display different modes of action. Communications Biology. 6: 677
Spens AE, Sutliff NA, Bennett SR, et al. (2023) Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction. Elife. 12
Wong CJ, Friedman SD, Snider L, et al. (2023) Validation of the association between MRI and gene signatures in facioscapulohumeral dystrophy muscle: implications for clinical trial design. Biorxiv : the Preprint Server For Biology
Nip Y, Bennett SR, Smith AA, et al. (2023) Human DUX4 and porcine DUXC activate similar early embryonic programs in pig muscle cells: implications for preclinical models of FSHD. Human Molecular Genetics
Crist SB, Nemkov T, Dumpit RF, et al. (2022) Unchecked oxidative stress in skeletal muscle prevents outgrowth of disseminated tumour cells. Nature Cell Biology
Wong CJ, Whiddon JL, Langford AT, et al. (2021) Canine DUXC: Implications for DUX4 retrotransposition and preclinical models of FSHD. Human Molecular Genetics
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