Roberto Zoncu, Ph.D.

Affiliations: 
Molecular and Cell Biology University of California, Berkeley, Berkeley, CA, United States 
 2007 Yale University, New Haven, CT 
Area:
How organelles sense nutrients and regulate cellular growth
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"Roberto Zoncu"
Mean distance: 15.5 (cluster 11)
 
SNBCP
Cross-listing: Cell Biology Tree

Parents

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Pietro De Camilli grad student 2007 Yale
 (Control of endocytosis by membrane phosphoinositides in living cells.)
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Publications

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Goul C, Peruzzo R, Zoncu R. (2023) The molecular basis of nutrient sensing and signalling by mTORC1 in metabolism regulation and disease. Nature Reviews. Molecular Cell Biology
Gupta S, Yano J, Mercier V, et al. (2021) Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth. Nature Cell Biology
Su MY, Fromm SA, Zoncu R, et al. (2020) Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD. Nature
Higuchi-Sanabria R, Shen K, Kelet N, et al. (2020) Lysosomal recycling of amino acids affects ER quality control. Science Advances. 6: eaaz9805
Shin HR, Zoncu R. (2020) The Lysosome at the Intersection of Cellular Growth and Destruction. Developmental Cell
Citron YR, Zoncu R. (2020) A zinc-sensing protein gives flies a gut feeling for growth. Nature. 580: 187-188
Lawrence RE, Fromm SA, Fu Y, et al. (2019) Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex. Science (New York, N.Y.)
Bersuker K, Hendricks J, Li Z, et al. (2019) The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis. Nature
Lim CY, Davis OB, Shin HR, et al. (2019) ER-lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signalling in Niemann-Pick type C. Nature Cell Biology
Lawrence RE, Zoncu R. (2019) The lysosome as a cellular centre for signalling, metabolism and quality control. Nature Cell Biology
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