Claude M. Schofield, Ph.D.

Affiliations: 
2005 Weill Cornell Medical College, New York, NY, United States 
Area:
GABA-A receptors
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"Claude Schofield"
Mean distance: 16.13 (cluster 11)
 
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Neil L. Harrison grad student 2005 Weill Cornell Medical College
 (Gating and modulation of recombinant glycine and gamma-aminobutyric acid type A receptors.)
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Publications

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Schofield CM, Kleiman-Weiner M, Rudolph U, et al. (2009) A gain in GABAA receptor synaptic strength in thalamus reduces oscillatory activity and absence seizures. Proceedings of the National Academy of Sciences of the United States of America. 106: 7630-5
Winsky-Sommerer R, Knapman A, Fedele DE, et al. (2008) Normal sleep homeostasis and lack of epilepsy phenotype in GABA A receptor alpha3 subunit-knockout mice. Neuroscience. 154: 595-605
Schofield CM, Huguenard JR. (2007) GABA affinity shapes IPSCs in thalamic nuclei. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7954-62
Jia F, Pignataro L, Schofield CM, et al. (2005) An extrasynaptic GABAA receptor mediates tonic inhibition in thalamic VB neurons. Journal of Neurophysiology. 94: 4491-501
Schofield CM, Harrison NL. (2005) Transmembrane residues define the action of isoflurane at the GABAA receptor alpha-3 subunit. Brain Research. 1032: 30-5
Jenkins A, Kash TL, Schofield CM, et al. (2005) Structural elements governing activation and modulation of GABAA receptors International Congress Series. 1283: 26-31
Schofield CM, Trudell JR, Harrison NL. (2004) Alanine-scanning mutagenesis in the signature disulfide loop of the glycine receptor alpha 1 subunit: critical residues for activation and modulation. Biochemistry. 43: 10058-63
Schofield CM, Jenkins A, Harrison NL. (2003) A highly conserved aspartic acid residue in the signature disulfide loop of the alpha 1 subunit is a determinant of gating in the glycine receptor. The Journal of Biological Chemistry. 278: 34079-83
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