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Irwin M. Liu, Ph.D.

Affiliations: 
2008 Pharmacology Duke University, Durham, NC 
Area:
Somatosensory
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"Irwin Liu"
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Fan Wang grad student 2008 Duke
 (A mechanism and pro-migratory function for non-canonical TGFbeta signaling through Smad1 and Smad5.)

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Liu I, Keir S, Rasheed BA, et al. (2011) Abstract 4417: Characterization of xenograft-derived EGFRvIII-positive GBM cell cultures reveals functional interactions between EGFRvIII, wild-type EGFR, and p53 Cancer Research. 71: 4417-4417
Schilling SH, Hjelmeland AB, Radiloff DR, et al. (2009) NDRG4 is required for cell cycle progression and survival in glioblastoma cells. The Journal of Biological Chemistry. 284: 25160-9
Liu IM, Schilling SH, Knouse KA, et al. (2009) TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch. The Embo Journal. 28: 88-98
Jian H, Shen X, Liu I, et al. (2006) Smad3-dependent nuclear translocation of beta-catenin is required for TGF-beta1-induced proliferation of bone marrow-derived adult human mesenchymal stem cells. Genes & Development. 20: 666-74
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