William T. Kimberly, Ph.D.
Affiliations: | 2004 | Harvard University, Cambridge, MA, United States |
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=1Google:
"William Kimberly"Mean distance: 17.66 (cluster 31) | S | N | B | C | P |
Parents
Sign in to add mentor| Dennis J. Selkoe | grad student | 2004 | Harvard | |
| (Intramembrane proteolysis and signal transduction: The gamma-secretase complex and its connection to Alzheimer's disease.) | ||||
BETA: Related publications
See more...
Publications
|
You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect. |
| Kimberly WT, Zheng JB, Town T, et al. (2005) Physiological regulation of the beta-amyloid precursor protein signaling domain by c-Jun N-terminal kinase JNK3 during neuronal differentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5533-43 |
| Fraering PC, LaVoie MJ, Ye W, et al. (2004) Detergent-dependent dissociation of active gamma-secretase reveals an interaction between Pen-2 and PS1-NTF and offers a model for subunit organization within the complex. Biochemistry. 43: 323-33 |
| Kimberly WT, Wolfe MS. (2003) Identity and function of gamma-secretase. Journal of Neuroscience Research. 74: 353-60 |
| Baulac S, LaVoie MJ, Kimberly WT, et al. (2003) Functional gamma-secretase complex assembly in Golgi/trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and gamma-secretase substrates. Neurobiology of Disease. 14: 194-204 |
| LaVoie MJ, Fraering PC, Ostaszewski BL, et al. (2003) Assembly of the gamma-secretase complex involves early formation of an intermediate subcomplex of Aph-1 and nicastrin. The Journal of Biological Chemistry. 278: 37213-22 |
| Walsh DM, Fadeeva JV, LaVoie MJ, et al. (2003) gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins. Biochemistry. 42: 6664-73 |
| Kimberly WT, Kovacs DM, Walsh D, et al. (2003) The 8th International Conference on Alzheimer's Disease and Related Disorders, July 20-25, 2002, Stockholm, Sweden. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 10: 51-61 |
| Kimberly WT, LaVoie MJ, Ostaszewski BL, et al. (2003) Gamma-secretase is a membrane protein complex comprised of presenilin, nicastrin, Aph-1, and Pen-2. Proceedings of the National Academy of Sciences of the United States of America. 100: 6382-7 |
| Kimberly WT, Esler WP, Ye W, et al. (2003) Notch and the amyloid precursor protein are cleaved by similar gamma-secretase(s). Biochemistry. 42: 137-44 |
| Micchelli CA, Esler WP, Kimberly WT, et al. (2003) Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 79-81 |