Allen C. Chen, Ph.D.
Affiliations: | 2009 | Harvard University, Cambridge, MA, United States |
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=1Google:
"Allen Chen"Mean distance: 17.66 (cluster 31) | S | N | B | C | P |
Parents
Sign in to add mentor| Dennis J. Selkoe | grad student | 2009 | Harvard | |
| (Aph-1 functions as a substrate docking site within the Alzheimer's disease relevant gamma -secretase complex.) | ||||
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Publications
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| Chen AC, Kim S, Shepardson N, et al. (2015) Physical and functional interaction between the α- and γ-secretases: A new model of regulated intramembrane proteolysis. The Journal of Cell Biology. 211: 1157-76 |
| Leriche G, Chen AC, Kim S, et al. (2015) A Fluorescent Analog of Batimastat Enables Imaging of α-Secretase in Living Cells. Acs Chemical Neuroscience |
| Chen AC, Guo LY, Ostaszewski BL, et al. (2010) Aph-1 associates directly with full-length and C-terminal fragments of gamma-secretase substrates. The Journal of Biological Chemistry. 285: 11378-91 |
| Young-Pearse TL, Chen AC, Chang R, et al. (2008) Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1. Neural Development. 3: 15 |
| Chen AC, Selkoe DJ. (2007) Response to: Pardossi-Piquard et al., "Presenilin-Dependent Transcriptional Control of the Abeta-Degrading Enzyme Neprilysin by Intracellular Domains of betaAPP and APLP." Neuron 46, 541-554. Neuron. 53: 479-83 |