Joshua P. Thaler, Ph.D.

Affiliations: 
2001 University of California, San Diego, La Jolla, CA 
Area:
Development
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"Joshua Thaler"
Mean distance: 15.8 (cluster 11)
 
SNBCP

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Samuel L. Pfaff grad student 2001 UCSD
 (How to make a motor neuron: 2 parts LIM, 1 part HB9 with a spritz of sonic.)
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Publications

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Banerjee J, Dorfman MD, Fasnacht R, et al. (2022) CX3CL1 Action on Microglia Protects from Diet-Induced Obesity by Restoring POMC Neuronal Excitability and Melanocortin System Activity Impaired by High-Fat Diet Feeding. International Journal of Molecular Sciences. 23
Dorfman MD, Frey J, Ness KM, et al. (2020) 212-OR: Testosterone Deficiency Increases Hypothalamic Gliosis and Metabolic Risk Diabetes. 69
Niraula A, Fasnacht R, Ness KM, et al. (2020) 1759-P: Prostaglandin PGE2 Receptor EP4 Signaling Deficiency in Microglia Reduces Weight Gain with Transient Glucose Improvements in Diet-Induced Obesity Diabetes. 69
Valdearcos M, Douglass JD, Robblee MM, et al. (2017) Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility. Cell Metabolism. 26: 185-197.e3
Douglass JD, Dorfman MD, Fasnacht R, et al. (2017) Astrocyte IKKβ/NF-κB signaling is required for diet-induced obesity and hypothalamic inflammation. Molecular Metabolism. 6: 366-373
Dorfman MD, Krull JE, Douglass JD, et al. (2017) Sex differences in microglial CX3CR1 signalling determine obesity susceptibility in mice. Nature Communications. 8: 14556
Dorfman MD, Krull JE, Scarlett JM, et al. (2017) Deletion of Protein Kinase C Lambda in POMC Neurons Predisposes to Diet-Induced Obesity. Diabetes
Douglass JD, Dorfman MD, Thaler JP. (2016) Glia: silent partners in energy homeostasis and obesity pathogenesis. Diabetologia
Meek TH, Nelson JT, Matsen ME, et al. (2016) Functional identification of a neurocircuit regulating blood glucose. Proceedings of the National Academy of Sciences of the United States of America
Dorfman MD, Thaler JP. (2015) Hypothalamic inflammation and gliosis in obesity. Current Opinion in Endocrinology, Diabetes, and Obesity. 22: 325-30
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