Jerri M. Rook, Ph.D.
Affiliations: | 2008 | Pharmacology, Toxicology & Therapeutics | University of Kansas, Lawrence, KS, United States |
Area:
pain neurobiologyGoogle:
"Jerri Rook"Mean distance: 17.56 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentor| Kenneth E. McCarson | grad student | 2008 | University of Kansas | |
| (Mechanisms of cutaneous wound healing are mediated via peripheral neuropeptide activity.) | ||||
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Publications
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| Qi A, Kling HE, Billard N, et al. (2023) . Molecular Pharmacology |
| Moehle MS, Bender AM, Dickerson JW, et al. (2021) Discovery of the First Selective M Muscarinic Acetylcholine Receptor Antagonists with Antiparkinsonian and Antidystonic Efficacy. Acs Pharmacology & Translational Science. 4: 1306-1321 |
| Spock M, Carter TR, Bollinger KA, et al. (2021) Discovery of VU6028418: A Highly Selective and Orally Bioavailable M Muscarinic Acetylcholine Receptor Antagonist. Acs Medicinal Chemistry Letters. 12: 1342-1349 |
| Moran SP, Xiang Z, Doyle CA, et al. (2019) Biased M receptor-positive allosteric modulators reveal role of phospholipase D in M-dependent rodent cortical plasticity. Science Signaling. 12 |
| Rook JM, Newhouse PA, Lindsley CW, et al. (2019) OPTIMIZATION OF NOVEL M1 PAMS FOR CLINICAL DEVELOPMENT WITH ENHANCED EFFICACY WHILE AVOIDING ADVERSE EFFECT LIABILITY FOR THE TREATMENT OF ALZHEIMER’S DISEASE Alzheimer's & Dementia. 15: P1592-P1593 |
| Engers JL, Childress ES, Long MF, et al. (2018) VU6007477, a Novel M PAM Based on a Pyrrolo[2,3-]pyridine Carboxamide Core Devoid of Cholinergic Adverse Events. Acs Medicinal Chemistry Letters. 9: 917-922 |
| Engers JL, Bender AM, Kalbfleisch JJ, et al. (2018) Discovery of tricyclic triazolo- and imidazopyridine lactams as M1 positive allosteric modulators (PAMs). Acs Chemical Neuroscience |
| Cieślik P, Woźniak M, Rook JM, et al. (2018) Mutual activation of glutamatergic mGlu and muscarinic M receptors reverses schizophrenia-related changes in rodents. Psychopharmacology |
| Bertron JL, Cho HP, Garcia-Barrantes PM, et al. (2018) The discovery of VU0486846: steep SAR from a series of M PAMs based on a novel benzomorpholine core. Bioorganic & Medicinal Chemistry Letters |
| Rook JM, Bertron JL, Cho HP, et al. (2018) A novel M1 PAM VU0486846 exerts efficacy in cognition models without displaying agonist activity or cholinergic toxicity. Acs Chemical Neuroscience |