Jeanna M. Wheeler, Ph.D.

Affiliations: 
2005 University of Washington, Seattle, Seattle, WA 
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"Jeanna Wheeler"
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James H. Thomas grad student 2005 University of Washington
 (Genetic analysis of rhythmic behavior in Caenorhabditis elegans.)
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Publications

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McMillan P, Wheeler J, Gatlin RE, et al. (2020) Adult onset pan-neuronal human tau tubulin kinase 1 expression causes severe cerebellar neurodegeneration in mice. Acta Neuropathologica Communications. 8: 200
Wheeler JM, McMillan P, Strovas TJ, et al. (2019) Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain. Science Translational Medicine. 11
Kow RL, Sikkema C, Wheeler JM, et al. (2017) Dopa Decarboxylase Modulates Tau Toxicity. Biological Psychiatry
Liachko NF, Saxton AD, McMillan PJ, et al. (2016) The phosphatase calcineurin regulates pathological TDP-43 phosphorylation. Acta Neuropathologica
Wheeler JM, McMillan PJ, Hawk M, et al. (2015) High copy wildtype human 1N4R tau expression promotes early pathological tauopathy accompanied by cognitive deficits without progressive neurofibrillary degeneration. Acta Neuropathologica Communications. 3: 33
McCormick AV, Wheeler JM, Guthrie CR, et al. (2013) Dopamine D2 receptor antagonism suppresses tau aggregation and neurotoxicity. Biological Psychiatry. 73: 464-71
Wheeler JM, Guthrie CR, Kraemer BC. (2012) Potential neuroprotective strategies against tauopathy Biochemical Society Transactions. 40: 656-660
Kraemer B, Guthrie C, Wheeler J. (2012) O1-07-04: Identifying protective strategies against tau neurotoxicity Alzheimer's & Dementia. 8: P97-P98
Wheeler JM, Guthrie CR, Kraemer BC. (2010) The role of MSUT-2 in tau neurotoxicity: A target for neuroprotection in tauopathy? Biochemical Society Transactions. 38: 973-976
Wheeler JM, Thomas JH. (2006) Identification of a novel gene family involved in osmotic stress response in Caenorhabditis elegans. Genetics. 174: 1327-36
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