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Roderick MacKinnon

Affiliations: 
Rockefeller University, New York, NY, United States 
Area:
Ion channels
Website:
https://www.rockefeller.edu/our-scientists/heads-of-laboratories/872-roderick-mackinnon/
Google:
"Roderick MacKinnon"
Bio:

The Nobel Prize in Chemistry 2003 was awarded "for discoveries concerning channels in cell membranes" jointly with one half to Peter Agre "for the discovery of water channels" and with one half to Roderick MacKinnon "for structural and mechanistic studies of ion channels".
http://www.nasonline.org/member-directory/members/3009152.html
http://lab.rockefeller.edu/mackinnon/
http://www.hhmi.org/scientists/roderick-mackinnon
http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2003/mackinnon-facts.html
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Mean distance: 14.1 (cluster 11)
 
SNBCP
Cross-listing: Chemistry Tree

Parents

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Christopher Miller post-doc 1989 Brandeis (Chemistry Tree)

Children

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Alexander R. Pico grad student 1998-2003 Rockefeller (Chemistry Tree)
Vanessa Ruta grad student 1999-2005 Rockefeller
Declan A. Doyle post-doc Rockefeller
Liang Feng post-doc Rockefeller
Richard K. Hite post-doc Rockefeller (Chemistry Tree)
Qiu-Xing Jiang post-doc
Youxing Jiang post-doc Rockefeller (Computational Biology Tree)
Seok-Yong Lee post-doc Rockefeller (Chemistry Tree)
Stephen B. Long post-doc (Chemistry Tree)
Eunyong Park post-doc (Cell Biology Tree)
Gonzalo Perez-Mitta post-doc Rockefeller (Chemistry Tree)
Rama Ranganathan post-doc Harvard Medical School (FlyTree)
Stephen G. Brohawn post-doc 2010- Rockefeller
Ji Sun post-doc 2014- Rockefeller (Chemistry Tree)
Chinfei Chen post-doc 1995-1996 Harvard Medical School
Kenton Jon Swartz post-doc 1993-1997 Harvard Medical School
Ming Zhou post-doc 1999-2004 Rockefeller (Chemistry Tree)

Collaborators

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Gary Yellen collaborator Harvard
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Publications

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Mandala VS, MacKinnon R. (2023) The membrane electric field regulates the PIP-binding site to gate the KCNQ1 channel. Proceedings of the National Academy of Sciences of the United States of America. 120: e2301985120
Tao X, Zhao C, MacKinnon R. (2023) Membrane protein isolation and structure determination in cell-derived membrane vesicles. Proceedings of the National Academy of Sciences of the United States of America. 120: e2302325120
Pérez-Mitta G, MacKinnon R. (2023) Freestanding lipid bilayer tensiometer for the study of mechanosensitive ion channels. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221541120
Mandala VS, MacKinnon R. (2022) Voltage-sensor movements in the Eag Kv channel under an applied electric field. Proceedings of the National Academy of Sciences of the United States of America. 119: e2214151119
Zhao C, MacKinnon R. (2022) Structural and functional analyses of a GPCR-inhibited ion channel TRPM3. Neuron
Zhang Y, Tao X, MacKinnon R. (2022) Correlation between structure and function in phosphatidylinositol lipid-dependent Kir2.2 gating. Proceedings of the National Academy of Sciences of the United States of America. 119: e2114046119
Zhao C, MacKinnon R. (2021) Molecular structure of an open human K channel. Proceedings of the National Academy of Sciences of the United States of America. 118
Niu Y, Tao X, Vaisey G, et al. (2021) Analysis of the mechanosensor channel functionality of TACAN. Elife. 10
Niu Y, Tao X, Touhara KK, et al. (2020) Cryo-EM analysis of PIP regulation in mammalian GIRK channels. Elife. 9
Niu Y, Tao X, Touhara KK, et al. (2020) Author response: Cryo-EM analysis of PIP2 regulation in mammalian GIRK channels Elife
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