Olga Azarenko, Ph.D.
Affiliations: | 2009 | Molecular, Cellular & Developmental Biology | University of California, Santa Barbara, Santa Barbara, CA, United States |
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"Olga Azarenko"Mean distance: 23748
Parents
Sign in to add mentor| Leslie Wilson | grad student | 2009 | UC Santa Barbara | |
| (Dietary isothiocyanates suppress microtubule dynamic instability in association with mitotic arrest and inhibition of tumor cell proliferation.) | ||||
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| Best RL, LaPointe NE, Azarenko O, et al. (2021) Microtubule and tubulin binding and regulation of microtubule dynamics by the antibody drug conjugate (ADC) payload, monomethyl auristatin E (MMAE): Mechanistic insights into MMAE ADC peripheral neuropathy. Toxicology and Applied Pharmacology. 115534 |
| Smiyun G, Azarenko O, Miller H, et al. (2017) βIII-tubulin enhances efficacy of cabazitaxel as compared with docetaxel. Cancer Chemotherapy and Pharmacology |
| Wilson L, Lopus M, Miller HP, et al. (2015) Effects of Eribulin on Microtubule Binding and Dynamic Instability Are Strengthened in the Absence of the βIII Tubulin Isotype. Biochemistry. 54: 6482-9 |
| Wilson L, Azarenko O, Smiyun G, et al. (2015) Abstract 1666: Increased sensitivity of βIII tubulin-containing microtubules to cabazitaxel compared with docetaxel: A possible role of βIII tubulin in specifying good efficacy of cabazitaxel for docetaxel-resistant tumors Cancer Research. 75: 1666-1666 |
| Azarenko O, Smiyun G, Mah J, et al. (2014) Antiproliferative mechanism of action of the novel taxane cabazitaxel as compared with the parent compound docetaxel in MCF7 breast cancer cells. Molecular Cancer Therapeutics. 13: 2092-103 |
| Azarenko O, Jordan MA, Wilson L. (2014) Erucin, the major isothiocyanate in arugula (Eruca sativa), inhibits proliferation of MCF7 tumor cells by suppressing microtubule dynamics. Plos One. 9: e100599 |
| Azarenko O, Smiyun G, Wilson L, et al. (2013) Abstract A300: Increased potency of the novel taxane cabazitaxel as compared with the parent compound docetaxel in MCF7 breast cancer cells. Molecular Cancer Therapeutics. 12 |
| Lopus M, Miller H, Azarenko O, et al. (2011) Abstract C215: Depletion of the resistance-associated βIII tubulin isotype enhances eribulin's potency in suppressing microtubule dynamic instability and promotes inhibition of both microtubule growth and shortening. Molecular Cancer Therapeutics. 10 |
| Smith JA, Wilson L, Azarenko O, et al. (2010) Eribulin binds at microtubule ends to a single site on tubulin to suppress dynamic instability. Biochemistry. 49: 1331-7 |
| Azarenko O, Okouneva T, Singletary KW, et al. (2008) Suppression of microtubule dynamic instability and turnover in MCF7 breast cancer cells by sulforaphane. Carcinogenesis. 29: 2360-8 |