Robert A. Nicholas

Affiliations: 
Neurobiology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pharmacology, Cell Biology
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"Robert Nicholas"
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Publications

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Boyer JL, Schachter JB, Sromek SM, et al. (2024) Avian and Human Homologues of the P2Y Receptor: Pharmacological, Signaling, and Molecular Properties. Drug Development Research. 39: 253-261
Singh A, Turner JM, Tomberg J, et al. (2020) Mutations in penicillin-binding protein 2 from cephalosporin-resistant Neisseria gonorrhoeae hinder ceftriaxone acylation by restricting protein dynamics. The Journal of Biological Chemistry
Singh A, Tomberg J, Nicholas RA, et al. (2019) Recognition of the β-lactam Carboxylate Triggers Acylation of Penicillin-Binding Protein 2. The Journal of Biological Chemistry
Vincent LR, Kerr SR, Tan Y, et al. (2018) -Selected Compensatory Mutations Restore the Fitness Cost of MosaicAlleles That Confer Ceftriaxone Resistance in. Mbio. 9
Rouquette-Loughlin CE, Zalucki YM, Dhulipala VL, et al. (2017) Control of gdhR Expression in Neisseria gonorrhoeae via Autoregulation and a Master Repressor (MtrR) of a Drug Efflux Pump Operon. Mbio. 8
Tomberg J, Fedarovich A, Vincent LR, et al. (2017) Alanine-501 Mutations in Penicillin-Binding Protein 2 from Neisseria gonorrhoeae: Structure, Mechanism, and Effects on Cephalosporin Resistance and Biological Fitness. Biochemistry
Nicholas RA. (2015) Insights into platelet P2Y12 receptor activation. Blood. 125: 893-5
Nandi S, Swanson S, Tomberg J, et al. (2015) Diffusion of antibiotics through the PilQ secretin in Neisseria gonorrhoeae occurs through the immature, sodium dodecyl sulfate-labile form. Journal of Bacteriology. 197: 1308-21
Fedarovich A, Cook E, Tomberg J, et al. (2014) Structural effect of the Asp345a insertion in penicillin-binding protein 2 from penicillin-resistant strains of Neisseria gonorrhoeae. Biochemistry. 53: 7596-603
Morrow GB, Nicholas RA, Kennedy C. (2014) UTP is not a biased agonist at human P2Y(11) receptors. Purinergic Signalling. 10: 581-5
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