Shengzhou Wu, MD, Ph.D

Affiliations: 
School of Optometry and Ophthalmology and Eye Hospital Wenzhou Medical College, Wenzhou Shi, Zhejiang Sheng, China 
Area:
NMDA channels, Serine racemase, ER stress, Calcium, Proteasome
Google:
"Shengzhou Wu"
Mean distance: 18.42 (cluster 41)
 
SNBCP

Parents

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Steven W. Barger grad student 2004 UAMS
 (Novel cell and tissue type expression of serine racemase: Implications for glial regulation of neurotransmission.)
Joy B. Snider post-doc Washington University School of Medicine
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Publications

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Wang Y, Lian M, Zhou J, et al. (2020) Brain Dicer1 Is Down-Regulated in a Mouse Model of Alzheimer's Disease Via Aβ42-Induced Repression of Nuclear Factor Erythroid 2-Related Factor 2. Molecular Neurobiology
Zhang H, Lu J, Wu S. (2020) Sp4 controls constitutive expression of neuronal serine racemase and NF-E2-related factor-2 mediates its induction by valproic acid. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. 194597
Zhou J, Song J, Wu S. (2019) Autophagic degradation of STIM2 mediates disruption of neuronal dendrites by ER stress. Journal of Neurochemistry
Zhang H, Song L, Chang Y, et al. (2017) Potential deficit from decreased cerebellar granule cell migration in serine racemase-deficient mice is reversed by increased expression of GluN2B and elevated levels of NMDAR agonists. Molecular and Cellular Neurosciences
Jiang H, Wu M, Liu Y, et al. (2017) Serine racemase deficiency attenuates choroidal neovascularization and reduces nitric oxide and VEGF levels by retinal pigment epithelial cells. Journal of Neurochemistry
Wu S, Barger SW. (2016) Disrupted-in-schizophrenia-1 as a broader link of glutamatergic transmission to schizophrenia impacts cerebral neurochemistry via the production of the 'gliotransmitter' d-serine, a NMDA receptor coagonist. Journal of Neurochemistry. 138: 503-505
Kuang XL, Liu Y, Chang Y, et al. (2016) Inhibition of store-operated calcium entry by sub-lethal levels of proteasome inhibition is associated with STIM1/STIM2 degradation. Cell Calcium
Klionsky DJ, Abdelmohsen K, Abe A, et al. (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222
Zhang H, Kuang XL, Chang Y, et al. (2015) Reduced serine racemase expression in aging rat cerebellum is associated with oxidative DNA stress and hypermethylation in the promoter. Brain Research
Jiang H, Wang X, Zhang H, et al. (2015) Loss-of-function mutation of serine racemase attenuates excitotoxicity by intravitreal injection of N-methyl-D-aspartate. Journal of Neurochemistry
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