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Andy N. Mead

Affiliations: 
Pfizer Ltd, UK, Sandwich, England, United Kingdom 
Area:
Drug addiction
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"Andy Mead"
Mean distance: 16.24 (cluster 6)
 
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Parents

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Dai Stephens grad student 1995-1999 University of Sussex
 (Andy spent a couple of stints in the lab, the first as grad student, the second as post doc)

Children

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Eoin C. OConnor grad student 2007-2011 Pfizer, Inc.

Collaborators

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Publications

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Jenkinson S, Goody SMG, Bassyouni A, et al. (2020) Translation of in vitro cannabinoid 1 receptor agonist activity to in vivo pharmacodynamic endpoints. Journal of Pharmacological and Toxicological Methods. 106899
Wager TT, Chappie TA, Horton D, et al. (2016) Dopamine D3/D2 Receptor Antagonist PF-4363467 Attenuates Opioid Drug-Seeking Behavior without Concomitant D2 Side Effects. Acs Chemical Neuroscience
Mead AN. (2014) Appropriate experimental approaches for predicting abuse potential and addictive qualities in preclinical drug discovery. Expert Opinion On Drug Discovery. 9: 1281-91
Horton DB, Potter DM, Mead AN. (2013) A translational pharmacology approach to understanding the predictive value of abuse potential assessments. Behavioural Pharmacology. 24: 410-36
O'Connor EC, Chapman K, Butler P, et al. (2011) The predictive validity of the rat self-administration model for abuse liability. Neuroscience and Biobehavioral Reviews. 35: 912-38
Tyszkiewicz CM, Mead A. (2011) Drug-induced anxiety and the elevated plus maze: Effect of lighting conditions Journal of Pharmacological and Toxicological Methods. 64: e24
O'Connor EC, Mead AN. (2010) Tramadol acts as a weak reinforcer in the rat self-administration model, consistent with its low abuse liability in humans. Pharmacology, Biochemistry, and Behavior. 96: 279-86
O'Connor EC, Crombag HS, Mead AN, et al. (2010) The mGluR5 antagonist MTEP dissociates the acquisition of predictive and incentive motivational properties of reward-paired stimuli in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1807-17
O'Connor EC, Parker D, Rollema H, et al. (2010) The alpha4beta2 nicotinic acetylcholine-receptor partial agonist varenicline inhibits both nicotine self-administration following repeated dosing and reinstatement of nicotine seeking in rats. Psychopharmacology. 208: 365-76
O’Connor EC, Crombag H, Mead A, et al. (2010) Incentive learning and the psychomotor activating effects of cocaine are controlled by mGluR5 in dopaminoceptive neurons F1000research. 1
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