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James A. Joseph, PhD, University of South Carolina

Affiliations:

USDA Human Nutrition Research Center on Aging

Area:

Mechanisms involved in brain aging and vulnerability to oxidative stress and inflammation; nutritional modulation of this sensitivity

Website:

http://www.hnrc.tufts.edu/1192109688818/HNRCA-Page-hnrca2w_1192109688908.html

Google:

"James Joseph"

Bio:

http://www.cmbm.org/mind_body_medicine_ABOUT/faculty_bios/James_Joseph_PhD.php

http://www.sfn.org/index.aspx?pagename=memberObituaries_joseph

Dr. Joseph received his Ph.D. in Behavioral Neuroscience from the University of South Carolina in 1976. He was a post-doctoral fellow at the Gerontology Research Center/NIH from 1976-1982, and a senior scientist at Lederle Research Laboratories from 1982-1985 when he joined the Armed Forces Radiobiology Institute. In 1988 he returned to the GRC as a senior scientist and in 1993 joined USDA Human Nutrition Research Center on Aging at Tufts University as the Director of the Neuroscience Laboratory.

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Parents

Children

Gemma Casadesus

grad student

Case Western

Collaborators

George Perry	collaborator		Case Western
Mark Anthony Smith	collaborator	2010	Case Western

BETA: Related publications

Publications

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Shukitt-Hale B, Bielinski DF, Lau FC, et al. (2015) The beneficial effects of berries on cognition, motor behaviour and neuronal function in ageing. The British Journal of Nutrition. 114: 1542-9
Shukitt-Hale B, Miller MG, Chu YF, et al. (2013) Coffee, but not caffeine, has positive effects on cognition and psychomotor behavior in aging. Age (Dordrecht, Netherlands). 35: 2183-92
Carey AN, Fisher DR, Joseph JA, et al. (2013) The ability of walnut extract and fatty acids to protect against the deleterious effects of oxidative stress and inflammation in hippocampal cells. Nutritional Neuroscience. 16: 13-20
Shukitt-Hale B, Lau FC, Cheng V, et al. (2013) Changes in gene expression in the rat hippocampus following exposure to 56Fe particles and protection by berry diets. Central Nervous System Agents in Medicinal Chemistry. 13: 36-42
Joseph JA, Casadesus G, Smith MA, et al. (2013) Nutrients and Food Constituents in Cognitive Decline and Neurodegenerative Disease Nutrition in the Prevention and Treatment of Disease. 373-390
Chang J, Rimando A, Pallas M, et al. (2012) Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer's disease. Neurobiology of Aging. 33: 2062-71
Elks CM, Reed SD, Mariappan N, et al. (2011) A blueberry-enriched diet attenuates nephropathy in a rat model of hypertension via reduction in oxidative stress. Plos One. 6: e24028
Malin DH, Lee DR, Goyarzu P, et al. (2011) Short-term blueberry-enriched diet prevents and reverses object recognition memory loss in aging rats. Nutrition (Burbank, Los Angeles County, Calif.). 27: 338-42
Crivello NA, Blusztajn JK, Joseph JA, et al. (2010) Short-term nutritional folate deficiency in rats has a greater effect on choline and acetylcholine metabolism in the peripheral nervous system than in the brain, and this effect escalates with age. Nutrition Research (New York, N.Y.). 30: 722-30
Joseph JA, Shukitt-Hale B, Brewer GJ, et al. (2010) Differential protection among fractionated blueberry polyphenolic families against DA-, Abeta(42)- and LPS-induced decrements in Ca(2+) buffering in primary hippocampal cells. Journal of Agricultural and Food Chemistry. 58: 8196-204