Richard M. Van Rijn, Ph.D.

Affiliations: 
2013- Medicinal Chemistry and Molecular Pharmacology Purdue University, West Lafayette, IN, United States 
Area:
opioid receptors, addiction, alcoholism
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"Richard Van Rijn"
Mean distance: 19.65 (cluster 6)
 
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Parents

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Robert Verpoorte research assistant 2001-2002 Leiden
Rob Leurs grad student 2002-2006 VU Amsterdam (Chemistry Tree)
Jennifer L. Whistler post-doc 2007-2013 UCSF

Children

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Robert Cassell grad student 2016- Purdue
Mee Jung Ko grad student 2016- Purdue
Arryn Blaine grad student 2018- Purdue
Anna Gutridge grad student 2018- Purdue
Yazan Meqbil grad student 2020- Purdue
Doungkamol Alongkronrusmee grad student 2014-2018 Purdue
Meridith T. Robins grad student 2014-2018 Purdue
Alexander French post-doc 2019- Purdue
Kamonchanok Sansuk post-doc 2013-2014 Purdue
Terrance Chiang research scientist 2013-2016 Purdue
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Publications

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French AR, Meqbil YJ, van Rijn RM. (2023) ClickArr: a novel, high-throughput assay for evaluating β-arrestin isoform recruitment. Frontiers in Pharmacology. 14: 1295518
Blaine AT, van Rijn RM. (2023) Receptor expression and signaling properties in the brain, and structural ligand motifs that contribute to delta opioid receptor agonist-induced seizures. Neuropharmacology. 109526
Hennessy MR, Gutridge AM, French AR, et al. (2023) Modified Akuamma Alkaloids with Increased Potency at the Mu-opioid Receptor. Journal of Medicinal Chemistry
Blaine AT, Miao Y, Yuan J, et al. (2022) Exploration of beta-arrestin isoform signaling pathways in delta opioid receptor agonist-induced convulsions. Frontiers in Pharmacology. 13: 914651
Van Rijn RM, Spetea M. (2022) Opioids and Their Receptors: Present and Emerging Concepts in Opioid Drug Discovery II. Molecules (Basel, Switzerland). 27
French AR, Gutridge AM, Yuan J, et al. (2022) Sex- and β-arrestin-dependent effects of kappa opioid receptor-mediated ethanol consumption. Pharmacology, Biochemistry, and Behavior. 216: 173377
French AR, van Rijn RM. (2022) An updated assessment of the translational promise of G-protein-biased kappa opioid receptor agonists to treat pain and other indications without debilitating adverse effects. Pharmacological Research. 177: 106091
Meqbil YJ, Su H, Cassell RJ, et al. (2021) Identification of a Novel Delta Opioid Receptor Agonist Chemotype with Potential Negative Allosteric Modulator Capabilities. Molecules (Basel, Switzerland). 26
Sharma KK, Cassell RJ, Meqbil YJ, et al. (2021) Modulating β-arrestin 2 recruitment at the δ- and μ-opioid receptors using peptidomimetic ligands. Rsc Medicinal Chemistry. 12: 1958-1967
Gutridge AM, Chakraborty S, Varga BR, et al. (2021) Evaluation of Kratom Opioid Derivatives as Potential Treatment Option for Alcohol Use Disorder. Frontiers in Pharmacology. 12: 764885
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