Marc Gielen
Affiliations: | NPP | University College London, London, United Kingdom |
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"Marc Gielen"Mean distance: 15.6 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| Pierre Paoletti | grad student | 2005-2009 | ENS Paris |
| Trevor G. Smart | post-doc | UCL |
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Publications
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| Prevost MS, Barilone N, Dejean de la Bâtie G, et al. (2023) An original potentiating mechanism revealed by the cryo-EM structures of the human α7 nicotinic receptor in complex with nanobodies. Nature Communications. 14: 5964 |
| Shi S, Lefebvre SN, Peverini L, et al. (2023) Illumination of a progressive allosteric mechanism mediating the glycine receptor activation. Nature Communications. 14: 795 |
| Merlaud Z, Marques X, Russeau M, et al. (2022) Conformational state-dependent regulation of GABA receptor diffusion and subsynaptic domains. Iscience. 25: 105467 |
| Gielen M, Barilone N, Corringer PJ. (2020) The desensitization pathway of GABA receptors, one subunit at a time. Nature Communications. 11: 5369 |
| Laverty D, Thomas P, Field M, et al. (2017) Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites. Nature Structural & Molecular Biology |
| Wilkins ME, Caley A, Gielen MC, et al. (2016) Murine startle mutant Nmf11 affects the structural stability of the glycine receptor and increases deactivation. The Journal of Physiology |
| Gielen M, Thomas P, Smart TG. (2015) The desensitization gate of inhibitory Cys-loop receptors. Nature Communications. 6: 6829 |
| Gielen MC, Lumb MJ, Smart TG. (2012) Benzodiazepines modulate GABAA receptors by regulating the preactivation step after GABA binding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5707-15 |
| Gielen M. (2010) [Molecular operation of ionotropic glutamate receptors: proteins that mediate the excitatory synaptic neurotransmission]. Mã©Decine Sciences : M/S. 26: 65-72 |
| Gielen M, Siegler Retchless B, Mony L, et al. (2009) Mechanism of differential control of NMDA receptor activity by NR2 subunits. Nature. 459: 703-7 |