William J. Bowers, Ph.D.
Affiliations: | Neurology, Center for Neural Development and Disease | University of Rochester Medical Center, Rochester, NY, United States |
Area:
CNS Gene Therapy, Immunotherapy, Neuroinflammation, Alzheimer's DiseaseGoogle:
"William Bowers"Mean distance: 17.45 (cluster 11)
Cross-listing: Alzheimer's Tree
Parents
Sign in to add mentor| Alanna Ruddell | grad student | 1990-1995 | University of Rochester Medical Center |
| Howard J. Federoff | post-doc | 1995-1999 | University of Rochester Medical Center |
Children
Sign in to add trainee| Michelle C. Janelsins | grad student | 2002-2008 | Rochester |
| Suresh de Silva | grad student | 2004-2010 | Rochester |
| Keigan M. Park | grad student | 2004-2010 | Rochester |
| Deborah A. Ryan | grad student | 2007-2010 | Rochester |
| Maya K. Desai | grad student | 2005-2011 | Rochester |
| Sara L. Montgomery | grad student | 2013 | Rochester |
BETA: Related publications
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Publications
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| Southwell AL, Franciosi S, Villanueva EB, et al. (2015) Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease. Neurobiology of Disease. 76: 46-56 |
| Evans EE, Jonason AS, Bussler H, et al. (2015) Antibody Blockade of Semaphorin 4D Promotes Immune Infiltration into Tumor and Enhances Response to Other Immunomodulatory Therapies. Cancer Immunology Research. 3: 689-701 |
| Smith ES, Jonason A, Reilly C, et al. (2014) SEMA4D compromises blood-brain barrier, activates microglia, and inhibits remyelination in neurodegenerative disease. Neurobiology of Disease. 73: 254-268 |
| Montgomery SL, Narrow WC, Mastrangelo MA, et al. (2013) Chronic neuron- and age-selective down-regulation of TNF receptor expression in triple-transgenic Alzheimer disease mice leads to significant modulation of amyloid- and Tau-related pathologies. The American Journal of Pathology. 182: 2285-97 |
| Montgomery SL, Bowers WJ. (2012) Tumor necrosis factor-alpha and the roles it plays in homeostatic and degenerative processes within the central nervous system. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 42-59 |
| Hadaczek P, Beyer J, Kells A, et al. (2011) Evaluation of an AAV2-based rapamycin-regulated glial cell line-derived neurotrophic factor (GDNF) expression vector system. Plos One. 6: e27728 |
| Schnell L, Hunanyan AS, Bowers WJ, et al. (2011) Combined delivery of Nogo-A antibody, neurotrophin-3 and the NMDA-NR2d subunit establishes a functional 'detour' in the hemisected spinal cord. The European Journal of Neuroscience. 34: 1256-67 |
| Hunter JM, Bowers WJ, Maarouf CL, et al. (2011) Biochemical and morphological characterization of the AβPP/PS/tau triple transgenic mouse model and its relevance to sporadic Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 27: 361-76 |
| Montgomery SL, Mastrangelo MA, Habib D, et al. (2011) Ablation of TNF-RI/RII expression in Alzheimer's disease mice leads to an unexpected enhancement of pathology: implications for chronic pan-TNF-α suppressive therapeutic strategies in the brain. The American Journal of Pathology. 179: 2053-70 |
| Domm W, Brooks L, Chung HL, et al. (2011) Robust antigen-specific humoral immune responses to sublingually delivered adenoviral vectors encoding HIV-1 Env: association with mucoadhesion and efficient penetration of the sublingual barrier. Vaccine. 29: 7080-9 |