Elisa A. Waxman, Ph.D.

Affiliations: 
2006 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Neuroscience Biology, Molecular Biology
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"Elisa Waxman"
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David R. Lynch grad student 2006 Penn
 (NMDA receptor biochemical and activity-dependent regulation of p38 MAPK and glutamate transporter EAAC1.)
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Publications

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Emmer KL, Waxman EA, Covy JP, et al. (2011) E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairment. The Journal of Biological Chemistry. 286: 35104-18
Waxman EA, Giasson BI. (2011) Induction of intracellular tau aggregation is promoted by α-synuclein seeds and provides novel insights into the hyperphosphorylation of tau. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7604-18
Waxman EA, Giasson BI. (2011) Characterization of kinases involved in the phosphorylation of aggregated α-synuclein. Journal of Neuroscience Research. 89: 231-47
Waxman EA, Giasson BI. (2010) A novel, high-efficiency cellular model of fibrillar alpha-synuclein inclusions and the examination of mutations that inhibit amyloid formation. Journal of Neurochemistry. 113: 374-88
Waxman EA, Emmer KL, Giasson BI. (2010) Residue Glu83 plays a major role in negatively regulating alpha-synuclein amyloid formation. Biochemical and Biophysical Research Communications. 391: 1415-20
Waxman EA, Mazzulli JR, Giasson BI. (2009) Characterization of hydrophobic residue requirements for alpha-synuclein fibrillization. Biochemistry. 48: 9427-36
Waxman EA, Covy JP, Bukh I, et al. (2009) Leucine-rich repeat kinase 2 expression leads to aggresome formation that is not associated with alpha-synuclein inclusions. Journal of Neuropathology and Experimental Neurology. 68: 785-96
Waxman EA, Giasson BI. (2009) Molecular mechanisms of alpha-synuclein neurodegeneration. Biochimica Et Biophysica Acta. 1792: 616-24
Waxman EA, Giasson BI. (2008) Specificity and regulation of casein kinase-mediated phosphorylation of alpha-synuclein. Journal of Neuropathology and Experimental Neurology. 67: 402-16
Waxman EA, Duda JE, Giasson BI. (2008) Characterization of antibodies that selectively detect alpha-synuclein in pathological inclusions. Acta Neuropathologica. 116: 37-46
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