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Mark E. Gurney

Affiliations: 
deCode Genetics Inc 
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"Mark Gurney"
Mean distance: 13.07 (cluster 17)
 
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Publications

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Butchbach ME, Singh J, Gurney ME, et al. (2014) The effect of diet on the protective action of D156844 observed in spinal muscular atrophy mice. Experimental Neurology. 256: 1-6
Butchbach ME, Singh J, Thorsteinsdóttir M, et al. (2010) Effects of 2,4-diaminoquinazoline derivatives on SMN expression and phenotype in a mouse model for spinal muscular atrophy. Human Molecular Genetics. 19: 454-67
Kiselyov AS, Gurney ME. (2010) Spinal muscular atrophy: Current therapeutic strategies Topics in Medicinal Chemistry. 6: 177-192
Singh J, Salcius M, Liu SW, et al. (2008) DcpS as a therapeutic target for spinal muscular atrophy. Acs Chemical Biology. 3: 711-22
Thurmond J, Butchbach ME, Palomo M, et al. (2008) Synthesis and biological evaluation of novel 2,4-diaminoquinazoline derivatives as SMN2 promoter activators for the potential treatment of spinal muscular atrophy. Journal of Medicinal Chemistry. 51: 449-69
Olsen MK, Roberds SL, Ellerbrock BR, et al. (2001) Disease mechanisms revealed by transcription profiling in SOD1-G93A transgenic mouse spinal cord. Annals of Neurology. 50: 730-40
Shin CM, Chung YH, Kim MJ, et al. (2000) Immunohistochemical study on the distribution of Bcl-2 and Bax in the central nervous system of the transgenic mice expressing a human Cu/Zn SOD mutation. Brain Research. 887: 309-15
Johnston JA, Dalton MJ, Gurney ME, et al. (2000) Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 97: 12571-6
Gurney ME, Tomasselli AG, Heinrikson RL. (2000) Neurobiology. Stay the executioner's hand. Science (New York, N.Y.). 288: 283-4
Cha CI, Chung YH, Shin CM, et al. (2000) Immunocytochemical study on the distribution of nitrotyrosine in the brain of the transgenic mice expressing a human Cu/Zn SOD mutation. Brain Research. 853: 156-61
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