Kimberly A. Scearce-Levie
Affiliations: | Genentech, Inc., San Francisco, CA, United States |
Area:
behavioral neuroscience, neurodegenerationGoogle:
"Kimberly Scearce-Levie"Mean distance: 13.56 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentor| René Hen | grad student | 1993-2002 | Columbia | |
| (Serotonin 1B receptor knockout mice as an animal model of vulnerability to drugs of abuse.) | ||||
| Lennart Mucke | post-doc | 2002-2007 | Gladstone Institute | |
Children
Sign in to add trainee| Hilary B. Gerstein | research assistant | 2004-2006 | Gladstone Institute of Neurological Disease |
BETA: Related publications
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Publications
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| Xia D, Lianoglou S, Sandmann T, et al. (2022) Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia. Molecular Neurodegeneration. 17: 41 |
| Ayalon G, Lee SH, Adolfsson O, et al. (2021) Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer's disease. Science Translational Medicine. 13 |
| Scearce-Levie K, Sanchez PE, Lewcock JW. (2020) Leveraging preclinical models for the development of Alzheimer disease therapeutics. Nature Reviews. Drug Discovery. 19: 447-462 |
| Hanson JE, Ma K, Elstrott J, et al. (2020) GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models. Cell Reports. 30: 381-396.e4 |
| Dominguez SL, Hegde GV, Hanson JE, et al. (2018) Antibody-mediated stabilization of NRG1 induces behavioral and electrophysiological alterations in adult mice. Scientific Reports. 8: 8239 |
| Le Pichon CE, Meilandt WJ, Dominguez S, et al. (2017) Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease. Science Translational Medicine. 9 |
| Wong K, Noubade R, Manzanillo P, et al. (2017) Mice deficient in NRROS show abnormal microglial development and neurological disorders. Nature Immunology |
| Weber M, Wu T, Meilandt WJ, et al. (2017) BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and rats. Scientific Reports. 7: 44249 |
| Villemure E, Volgraf M, Jiang Y, et al. (2017) GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile. Acs Medicinal Chemistry Letters. 8: 84-89 |
| Ertürk A, Mentz S, Stout EE, et al. (2016) Interfering with the Chronic Immune Response Rescues Chronic Degeneration After Traumatic Brain Injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 9962-75 |