Jill M. Weimer, Ph.D.

Affiliations: 
2006 University of Rochester, Rochester, NY 
Area:
Neuroscience Biology
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"Jill Weimer"
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Eva Anton grad student
Howard J. Federoff grad student 2006 Rochester
 (Systematic analysis of cellular and behavioural changes in the Cln3-/- mouse model of Batten disease.)
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Publications

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Leppert HG, Anderson JT, Timm KJ, et al. (2023) Sortilin inhibition treats multiple neurodegenerative lysosomal storage disorders. Biorxiv : the Preprint Server For Biology
Centa JL, Stratton MP, Pratt MA, et al. (2023) Protracted CLN3 Batten disease in mice that genetically model an exon-skipping therapeutic approach. Molecular Therapy. Nucleic Acids. 33: 15-27
Swier VJ, White KA, Johnson TB, et al. (2023) A novel porcine model of CLN3 Batten disease recapitulates clinical phenotypes. Disease Models & Mechanisms
Johnson TB, Brudvig JJ, Likhite S, et al. (2023) Early postnatal administration of an AAV9 gene therapy is safe and efficacious in CLN3 disease. Frontiers in Genetics. 14: 1118649
Holmes AD, White KA, Pratt MA, et al. (2022) Sex-split analysis of pathology and motor-behavioral outcomes in a mouse model of CLN8-Batten disease reveals an increased disease burden and trajectory in female Cln8 mice. Orphanet Journal of Rare Diseases. 17: 411
Brudvig JJ, Swier VJ, Johnson TB, et al. (2022) Glycerophosphoinositol is Elevated in Blood Samples From pigs, Mice, and CLN3-Affected Individuals. Biomarker Insights. 17: 11772719221107765
Swier VJ, White KA, Johnson TB, et al. (2022) A Novel Porcine Model of CLN2 Batten Disease that Recapitulates Patient Phenotypes. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics
Rechtzigel MJ, Meyerink BL, Leppert H, et al. (2022) Transmembrane Batten Disease Proteins Interact With a Shared Network of Vesicle Sorting Proteins, Impacting Their Synaptic Enrichment. Frontiers in Neuroscience. 16: 834780
Brudvig JJ, Weimer JM. (2022) CLN7 gene therapy: hope for an ultra-rare condition. The Journal of Clinical Investigation. 132
Muthusamy N, Williams TI, O'Toole R, et al. (2022) Phosphorylation-dependent proteome of Marcks in ependyma during aging and behavioral homeostasis in the mouse forebrain. Geroscience
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