Alexandros Tzatsos, Ph.D.

Affiliations: 
2006 Boston University, Boston, MA, United States 
Area:
Molecular Biology
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"Alexandros Tzatsos"
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Parents

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Konstantin V. Kandror grad student 2006 Boston University
 (The role of mammalian target of rapamycin (mTOR) in insulin resistance.)
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Publications

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Sun J, Cai X, Yung MM, et al. (2018) miR-137 mediates the functional link between c-Myc and EZH2 that regulates cisplatin resistance in ovarian cancer. Oncogene
Meng Y, Chen CW, Yung MMH, et al. (2018) DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer. Cancer Letters
Andricovich J, Perkail S, Kai Y, et al. (2018) Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors. Cancer Cell. 33: 512-526.e8
Andricovich J, Kai Y, Tzatsos A. (2016) Lysine-specific histone demethylases in normal and malignant hematopoiesis. Experimental Hematology
Andricovich J, Kai Y, Peng W, et al. (2016) Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis. The Journal of Clinical Investigation. 126: 905-20
Gao T, Zhou D, Yang C, et al. (2013) Hippo signaling regulates differentiation and maintenance in the exocrine pancreas. Gastroenterology. 144: 1543-53, 1553.e1
Tzatsos A, Paskaleva P, Ferrari F, et al. (2013) KDM2B promotes pancreatic cancer via Polycomb-dependent and -independent transcriptional programs. The Journal of Clinical Investigation. 123: 727-39
Tzatsos A, Paskaleva P, Lymperi S, et al. (2011) Lysine-specific demethylase 2B (KDM2B)-let-7-enhancer of zester homolog 2 (EZH2) pathway regulates cell cycle progression and senescence in primary cells. The Journal of Biological Chemistry. 286: 33061-9
Corcoran RB, Contino G, Deshpande V, et al. (2011) STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis. Cancer Research. 71: 5020-9
Gurumurthy S, Xie SZ, Alagesan B, et al. (2010) The Lkb1 metabolic sensor maintains haematopoietic stem cell survival. Nature. 468: 659-63
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