Seth Shatkin Margolis, Ph.D.

Affiliations: 
Neurobiology JHMI, Baltimore, MD, United States 
Area:
Neurobiology
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"Seth Margolis"
Mean distance: 14.32 (cluster 11)
 
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Publications

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Türker F, Margolis SS. (2023) Proteasome cap particle regulates synapses. Science (New York, N.Y.). 380: 795-796
He HY, Ahsan A, Bera R, et al. (2023) Neuronal membrane proteasomes regulate neuronal circuit activity in vivo and are required for learning-induced behavioral plasticity. Proceedings of the National Academy of Sciences of the United States of America. 120: e2216537120
Sell GL, Xin W, Cook EK, et al. (2021) Deleting a UBE3A substrate rescues impaired hippocampal physiology and learning in Angelman syndrome mice. Scientific Reports. 11: 19414
Shin NY, Yamazaki H, Beniash E, et al. (2020) Amelogenin phosphorylation regulates tooth enamel formation by stabilizing a transient amorphous mineral precursor. The Journal of Biological Chemistry
Schaffer TB, Smith JE, Cook EK, et al. (2018) PKCε Inhibits Neuronal Dendritic Spine Development through Dual Phosphorylation of Ephexin5. Cell Reports. 25: 2470-2483.e8
Ramachandran KV, Fu JM, Schaffer TB, et al. (2018) Activity-Dependent Degradation of the Nascentome by the Neuronal Membrane Proteasome. Molecular Cell. 71: 169-177.e6
Sell GL, Schaffer TB, Margolis SS. (2017) Reducing expression of synapse-restricting protein Ephexin5 ameliorates Alzheimer's-like impairment in mice. The Journal of Clinical Investigation
Ramachandran KV, Margolis SS. (2017) A mammalian nervous-system-specific plasma membrane proteasome complex that modulates neuronal function. Nature Structural & Molecular Biology
Hamilton AM, Lambert JT, Parajuli LK, et al. (2017) A dual role for the RhoGEF Ephexin5 in regulation of dendritic spine outgrowth. Molecular and Cellular Neurosciences
Sell GL, Margolis SS. (2015) From UBE3A to Angelman syndrome: a substrate perspective. Frontiers in Neuroscience. 9: 322
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