Emer M. Smyth, Ph.D.

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
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"Emer Smyth"
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Alexander Frey grad student 2013 Penn
Edward P. Chen grad student 2014 Penn
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Publications

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Siangjong L, Goldman DH, Kriska T, et al. (2015) Vascular hepoxilin and trioxilins mediate vasorelaxation through TP receptor inhibition in mouse arteries. Acta Physiologica (Oxford, England)
Markosyan N, Rech A, Vonderheide RH, et al. (2015) Abstract 469: mPGES1 deletion and the mechanisms of tumor growth suppression Cancer Research. 75: 469-469
Markosyan N, Chen EP, Smyth EM. (2014) Targeting COX-2 abrogates mammary tumorigenesis: Breaking cancer-associated suppression of immunosurveillance. Oncoimmunology. 3: e29287
Khan A, Li D, Ibrahim S, et al. (2014) The physical association of the P2Y12 receptor with PAR4 regulates arrestin-mediated akt activation Molecular Pharmacology. 86: 1-11
Chen EP, Markosyan N, Connolly E, et al. (2014) Myeloid Cell COX-2 deletion reduces mammary tumor growth through enhanced cytotoxic T-lymphocyte function. Carcinogenesis. 35: 1788-97
Markosyan N, Smyth EM. (2014) Abstract 928: Deletion of mammary epithelial mPGES1 suppresses tumor development in mice: a possible effect of substrate re-diversion Cancer Research. 74: 928-928
Markosyan N, Chen EP, Evans RA, et al. (2013) Mammary carcinoma cell derived cyclooxygenase 2 suppresses tumor immune surveillance by enhancing intratumoral immune checkpoint activity. Breast Cancer Research : Bcr. 15: R75
Frey AJ, Ibrahim S, Gleim S, et al. (2013) Biased suppression of TP homodimerization and signaling through disruption of a TM GxxxGxxxL helical interaction motif. Journal of Lipid Research. 54: 1678-90
Siangjong L, Gauthier KM, Pfister SL, et al. (2013) Endothelial 12(S)-HETE vasorelaxation is mediated by thromboxane receptor inhibition in mouse mesenteric arteries. American Journal of Physiology. Heart and Circulatory Physiology. 304: H382-92
Ibrahim S, McCartney A, Markosyan N, et al. (2013) Heterodimerization with the prostacyclin receptor triggers thromboxane receptor relocation to lipid rafts. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 60-6
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