Tod A. Leighfield, Ph.D.

Affiliations: 
2013 Medical University of South Carolina, Charleston, SC, United States 
Area:
Toxicology, General Chemistry, General Biology
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"Tod Leighfield"
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John S. Ramsdell grad student 2013 MUSC
 (The distribution and elimination of lipid and amino acid brevetoxin conjugates.)
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Publications

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Leighfield TA, Muha N, Ramsdell JS. (2014) Tissue distribution of amino acid- and lipid-brevetoxins after intravenous administration to C57BL/6 mice. Chemical Research in Toxicology. 27: 1166-75
Henri JO, Leighfield TA, Lanceleur R, et al. (2014) Permeability of dihydro- and cysteine-brevetoxin metabolites across a Caco-2 cell monolayer Harmful Algae. 32: 22-26
Leighfield TA, Muha N, Miles CO, et al. (2013) Semisynthesis of radiolabeled amino acid and lipid brevetoxin metabolites and their blood elimination kinetics in C57BL/6 mice. Chemical Research in Toxicology. 26: 868-77
Twiner MJ, Flewelling LJ, Fire SE, et al. (2012) Comparative analysis of three brevetoxin-associated bottlenose dolphin (Tursiops truncatus) mortality events in the Florida Panhandle region (USA). Plos One. 7: e42974
Van Dolah FM, Fire SE, Leighfield TA, et al. (2012) Determination of paralytic shellfish toxins in shellfish by receptor binding assay: collaborative study. Journal of Aoac International. 95: 795-812
Leighfield TA, Muha N, Ramsdell JS. (2009) Brevetoxin B is a clastogen in rats, but lacks mutagenic potential in the SP-98/100 Ames test. Toxicon : Official Journal of the International Society On Toxinology. 54: 851-6
Goldstein T, Zabka TS, Delong RL, et al. (2009) The role of domoic acid in abortion and premature parturition of California sea lions (Zalophus californianus) on San Miguel Island, California. Journal of Wildlife Diseases. 45: 91-108
Fire SE, Wang Z, Leighfield TA, et al. (2009) Domoic acid exposure in pygmy and dwarf sperm whales (Kogia spp.) from southeastern and mid-Atlantic U.S. waters Harmful Algae. 8: 658-664
Morton SL, Vershinin A, Smith LL, et al. (2009) Seasonality of Dinophysis spp. and Prorocentrum lima in Black Sea phytoplankton and associated shellfish toxicity Harmful Algae. 8: 629-636
Goldstein T, Mazet JA, Zabka TS, et al. (2008) Novel symptomatology and changing epidemiology of domoic acid toxicosis in California sea lions (Zalophus californianus): an increasing risk to marine mammal health. Proceedings. Biological Sciences / the Royal Society. 275: 267-76
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