Tom N. Grammatopoulos, Ph.D.
Affiliations: | 2002 | University of Illinois, Urbana-Champaign, Urbana-Champaign, IL |
Area:
Cell Biology, Neuroscience BiologyGoogle:
"Tom Grammatopoulos"Mean distance: 35622
Parents
Sign in to add mentor| James A. Weyhenmeyer | grad student | 2002 | UIUC | |
| (Angiotensin's role in hypoxic injury.) | ||||
| David G. Standaert | post-doc | 2004-2006 | Harvard Medical School | |
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Publications
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| Grammatopoulos TN, Outeiro TF, Hyman BT, et al. (2007) Angiotensin II protects against alpha-synuclein toxicity and reduces protein aggregation in vitro. Biochemical and Biophysical Research Communications. 363: 846-51 |
| Outeiro TF, Grammatopoulos TN, Altmann S, et al. (2007) Pharmacological inhibition of PARP-1 reduces alpha-synuclein- and MPP+-induced cytotoxicity in Parkinson's disease in vitro models. Biochemical and Biophysical Research Communications. 357: 596-602 |
| St Martin JL, Klucken J, Outeiro TF, et al. (2007) Dopaminergic neuron loss and up-regulation of chaperone protein mRNA induced by targeted over-expression of alpha-synuclein in mouse substantia nigra. Journal of Neurochemistry. 100: 1449-57 |
| Grammatopoulos TN, Jones SM, Ahmadi FA, et al. (2007) Angiotensin type 1 receptor antagonist losartan, reduces MPTP-induced degeneration of dopaminergic neurons in substantia nigra. Molecular Neurodegeneration. 2: 1 |
| Grammatopoulos TN, Ahmadi F, Jones SM, et al. (2005) Angiotensin II protects cultured midbrain dopaminergic neurons against rotenone-induced cell death. Brain Research. 1045: 64-71 |
| Grammatopoulos TN, Johnson V, Moore SA, et al. (2004) Angiotensin type 2 receptor neuroprotection against chemical hypoxia is dependent on the delayed rectifier K+ channel, Na+/Ca2+ exchanger and Na+/K+ ATPase in primary cortical cultures. Neuroscience Research. 50: 299-306 |
| Jing G, Grammatopoulos T, Ferguson P, et al. (2004) Inhibitory effects of angiotensin on NMDA-induced cytotoxicity in primary neuronal cultures. Brain Research Bulletin. 62: 397-403 |
| Moore SA, Huang N, Hinthong O, et al. (2004) Human angiotensin II type-2 receptor inhibition of insulin-mediated ERK-2 activity via a G-protein coupled signaling pathway. Brain Research. Molecular Brain Research. 124: 62-9 |
| Grammatopoulos TN, Morris K, Bachar C, et al. (2004) Angiotensin II attenuates chemical hypoxia-induced caspase-3 activation in primary cortical neuronal cultures. Brain Research Bulletin. 62: 297-303 |
| Ahmadi FA, Linseman DA, Grammatopoulos TN, et al. (2003) The pesticide rotenone induces caspase-3-mediated apoptosis in ventral mesencephalic dopaminergic neurons. Journal of Neurochemistry. 87: 914-21 |