Mitchell Ho, Ph.D.

Affiliations: 
2002 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Immunology, Molecular Biology, Neuroscience Biology
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"Mitchell Ho"
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Parents

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Mariangela Segre grad student 2002 UIUC
 (Mimicry of cocaine by anti -idiotypic antibodies: Molecular basis and antagonist drug design.)
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Publications

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Zhang H, Deng M, Pei F, et al. (2019) Next-Generation Antibody Therapeutics: Discovery, Development and Beyond: highlights of the third annual conference of the Chinese Antibody Society. Antibody Therapeutics. 2: 99-107
Zhang YF, Ho M. (2017) Humanization of rabbit monoclonal antibodies via grafting combined Kabat/IMGT/Paratome complementarity-determining regions: rationale and examples. Mabs. 0
Zhang YF, Ho M. (2016) Humanization of high-affinity antibodies targeting glypican-3 in hepatocellular carcinoma. Scientific Reports. 6: 33878
Zhang YF, Phung Y, Gao W, et al. (2015) New high affinity monoclonal antibodies recognize non-overlapping epitopes on mesothelin for monitoring and treating mesothelioma. Scientific Reports. 5: 9928
Tang Z, Feng M, Gao W, et al. (2013) A human single-domain antibody elicits potent antitumor activity by targeting an epitope in mesothelin close to the cancer cell surface. Molecular Cancer Therapeutics. 12: 416-26
Phung Y, Gao W, Man YG, et al. (2012) High-affinity monoclonal antibodies to cell surface tumor antigen glypican-3 generated through a combination of peptide immunization and flow cytometry screening. Mabs. 4: 592-9
Feng Y, Xiao X, Zhu Z, et al. (2009) A novel human monoclonal antibody that binds with high affinity to mesothelin-expressing cells and kills them by antibody-dependent cell-mediated cytotoxicity. Molecular Cancer Therapeutics. 8: 1113-8
Ho M, Pastan I. (2009) In vitro antibody affinity maturation targeting germline hotspots. Methods in Molecular Biology (Clifton, N.J.). 525: 293-308, xiv
Ho M, Pastan I. (2009) Mammalian cell display for antibody engineering. Methods in Molecular Biology (Clifton, N.J.). 525: 337-52, xiv
Ho M, Nagata S, Pastan I. (2006) Isolation of anti-CD22 Fv with high affinity by Fv display on human cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 9637-42
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