Neal G. Simon

Affiliations: 
Lehigh University, Bethlehem, PA, United States 
Area:
Cell Biology, Neuroscience Biology, Molecular Biology
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"Neal Simon"
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Publications

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Difede J, McAleavey AA, Emrich M, et al. (2023) A proof-of-concept randomized crossover clinical trial of a first-in-class vasopressin 1a receptor antagonist for PTSD: Design, methods, and recruitment. Contemporary Clinical Trials Communications. 33: 101116
Lago T, Brownstein M, Beydler E, et al. (2020) Effects of SRX246, a Vasopressin 1a Receptor (V1a) Antagonist, on an Experimental Model of Phasic and Sustained Threat in Humans Biological Psychiatry. 87: S167-S168
Morrison TR, Kulkarni P, Cai X, et al. (2019) Treating Head Injury using a Novel Vasopressin 1a Receptor Antagonist. Neuroscience Letters. 134565
Lee RJ, Coccaro EF, Cremers H, et al. (2013) A novel V1a receptor antagonist blocks vasopressin-induced changes in the CNS response to emotional stimuli: an fMRI study. Frontiers in Systems Neuroscience. 7: 100
Fabio KM, Guillon CD, Lu SF, et al. (2013) Pharmacokinetics and metabolism of SRX246: a potent and selective vasopressin 1a antagonist. Journal of Pharmaceutical Sciences. 102: 2033-43
Fabio K, Guillon C, Lacey CJ, et al. (2012) Synthesis and evaluation of potent and selective human V1a receptor antagonists as potential ligands for PET or SPECT imaging. Bioorganic & Medicinal Chemistry. 20: 1337-45
Mo Q, Lu S, Garippa C, et al. (2009) Genome-wide analysis of DHEA- and DHT-induced gene expression in mouse hypothalamus and hippocampus. The Journal of Steroid Biochemistry and Molecular Biology. 114: 135-43
Ferris CF, Stolberg T, Kulkarni P, et al. (2008) Imaging the neural circuitry and chemical control of aggressive motivation. Bmc Neuroscience. 9: 111
Simon NG, Guillon C, Fabio K, et al. (2008) Vasopressin antagonists as anxiolytics and antidepressants: recent developments. Recent Patents On Cns Drug Discovery. 3: 77-93
Guillon CD, Koppel GA, Brownstein MJ, et al. (2007) Azetidinones as vasopressin V1a antagonists. Bioorganic & Medicinal Chemistry. 15: 2054-80
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