Christopher Major, Ph.D.
Affiliations: | 2000 | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Cell Biology, Molecular BiologyGoogle:
"Christopher Major"Mean distance: 23748
Parents
Sign in to add mentor| Bryan A. Wolf | grad student | 2000 | Penn | |
| (Cytokines and type 1 diabetes: Role of cytokine mediated signal transduction pathways in pancreatic beta cell dysfunction.) | ||||
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Publications
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| Major CD, Wolf BA. (2001) Interleukin-1beta stimulation of c-Jun NH(2)-terminal kinase activity in insulin-secreting cells: evidence for cytoplasmic restriction. Diabetes. 50: 2721-8 |
| Major CD, Gao ZY, Wolf BA. (1999) Activation of the sphingomyelinase/ceramide signal transduction pathway in insulin-secreting beta-cells: role in cytokine-induced beta-cell death. Diabetes. 48: 1372-80 |
| Alter CA, Amagasu M, Shah K, et al. (1994) U-73122 does not specifically inhibit phospholipase C in rat pancreatic islets and insulin-secreting beta-cell lines. Life Sciences. 54: PL107-12 |
| Konrad RJ, Major CD, Wolf BA. (1994) Diacylglycerol hydrolysis to arachidonic acid is necessary for insulin secretion from isolated pancreatic islets: sequential actions of diacylglycerol and monoacylglycerol lipases. Biochemistry. 33: 13284-94 |
| Major C, Wolf BA. (1994) Quantitation of the fatty acid composition of phosphatidic acid by capillary gas chromatography electron-capture detection with picomole sensitivity. Journal of Chromatography. B, Biomedical Applications. 658: 233-40 |
| Konrad RJ, Jolly YC, Major C, et al. (1993) Fuel secretagogue stimulation of arachidonic acid accumulation in fresh and cultured pancreatic islets. Molecular and Cellular Endocrinology. 92: 135-40 |
| Jolly YC, Major C, Wolf BA. (1993) Transient activation of calcium-dependent phospholipase A2 by insulin secretagogues in isolated pancreatic islets. Biochemistry. 32: 12209-17 |
| Konrad RJ, Jolly YC, Major C, et al. (1992) Inhibition of phospholipase A2 and insulin secretion in pancreatic islets. Biochimica Et Biophysica Acta. 1135: 215-20 |
| Konrad RJ, Jolly YC, Major C, et al. (1992) Carbachol stimulation of phospholipase A2 and insulin secretion in pancreatic islets. The Biochemical Journal. 287: 283-90 |