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Christina K. Speirs, Ph.D.

Affiliations: 
2009 Vanderbilt University, Nashville, TN 
Area:
Genetics
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"Christina Speirs"
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Lilianna Solnica-Krezel grad student 2009 Vanderbilt
 (Prostaglandin Gbetagamma signaling stimulates gastrulation movements by limiting cell adhesion through Snail stabilization.)

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Publications

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Contreras J, Lin A, Weiner A, et al. (2018) (P37) Radiation-Induced Immunosuppression in Locally Advanced Non-Small Cell Lung Cancer: Another Cardiac Toxicity? International Journal of Radiation Oncology Biology Physics. 101
Sun Y, Zheng S, Torossian A, et al. (2012) Role of insulin-like growth factor-1 signaling pathway in cisplatin-resistant lung cancer cells. International Journal of Radiation Oncology, Biology, Physics. 82: e563-72
Kim KW, Speirs CK, Jung DK, et al. (2011) The zinc ionophore PCI-5002 radiosensitizes non-small cell lung cancer cells by enhancing autophagic cell death. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 6: 1542-52
Sun Y, Moretti L, Giacalone NJ, et al. (2011) Inhibition of JAK2 signaling by TG101209 enhances radiotherapy in lung cancer models. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 6: 699-706
Kim SH, Speirs CK, Solnica-Krezel L, et al. (2011) Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin. Disease Models & Mechanisms. 4: 255-67
Speirs CK, Jernigan KK, Kim SH, et al. (2010) Prostaglandin Gbetagamma signaling stimulates gastrulation movements by limiting cell adhesion through Snai1a stabilization. Development (Cambridge, England). 137: 1327-37
Sun Y, Zheng S, Speirs C, et al. (2010) Gene Profiling of Cancer Stem Cells-like Cells Reveals IGF-1R and IGFBP3 Pathway as a Promising Therapeutic Target for Lung Cancer International Journal of Radiation Oncology*Biology*Physics. 78: S131
Geng X, Speirs C, Lagutin O, et al. (2008) Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly. Developmental Cell. 15: 236-47
Geng X, Speirs C, Lagutin O, et al. (2008) Six3-promoted holoprosencephaly is caused by the absence of Shh expression in the rostral diencephalon ventral midline Developmental Biology. 319: 594
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