John Orlowski

Affiliations: 
McGill University, Montreal, QC, Canada 
Area:
Animal Physiology Biology, Neuroscience Biology, Pharmacology
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"John Orlowski"
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Publications

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Freeman SA, Grinstein S, Orlowski J. (2022) Determinants, Maintenance and Function of Organellar pH. Physiological Reviews
Dong Y, Li H, Ilie A, et al. (2022) Structural basis of autoinhibition of the human NHE3-CHP1 complex. Science Advances. 8: eabn3925
Dong Y, Gao Y, Ilie A, et al. (2021) Structure and mechanism of the human NHE1-CHP1 complex. Nature Communications. 12: 3474
Petitjean H, Fatima T, Mouchbahani-Constance S, et al. (2020) Loss of SLC9A6/NHE6 impairs nociception in a mouse model of Christianson Syndrome. Pain
Ilie A, Boucher A, Park J, et al. (2020) Assorted dysfunctions of endosomal alkali cation/proton exchanger SLC9A6 variants linked to Christianson syndrome. The Journal of Biological Chemistry
Rajah A, Boudreau CG, Ilie A, et al. (2019) Paxillin S273 Phosphorylation Regulates Adhesion Dynamics and Cell Migration through a Common Protein Complex with PAK1 and βPIX. Scientific Reports. 9: 11430
Gao AYL, Ilie A, Chang PKY, et al. (2019) A Christianson syndrome-linked deletion mutation (Δ287ES288) in SLC9A6 impairs hippocampal neuronal plasticity. Neurobiology of Disease. 104490
Ilie A, Gao AYL, Boucher A, et al. (2018) A potential gain-of-function variant of SLC9A6 leads to endosomal alkalinization and neuronal atrophy associated with Christianson Syndrome. Neurobiology of Disease
Orlowski J. (2017) SMAD5 signaling: more than meets the nuclei. Cell Research
Jinadasa T, Josephson CB, Boucher A, et al. (2015) Determinants of Cation Permeation and Drug Sensitivity in Predicted Transmembrane Helix 9 and Adjoining Exofacial Re-entrant Loop 5 of Na+/H+ Exchanger NHE1. The Journal of Biological Chemistry. 290: 18173-86
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