Trevor M. Lewis
Affiliations: | The University of New South Wales, Australia |
Area:
Ligand gated ion channels, glycine receptorsGoogle:
"Trevor Lewis"Mean distance: 15.22 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| David Colquhoun | post-doc | 1994-1997 | UCL |
| Peter R. Schofield | post-doc | 1997-2003 | Garvan Institute |
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Publications
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| Indurthi DC, Qudah T, Liao VW, et al. (2018) Revisiting autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) mutations in the nicotinic acetylcholine receptor reveal an increase in efficacy regardless of stochiometry. Pharmacological Research |
| Indurthi DC, Lewis TM, Ahring PK, et al. (2016) Ligand Binding at the 4-4 Agonist-Binding Site of the 42 nAChR Triggers Receptor Activation through a Pre-Activated Conformational State. Plos One. 11: e0161154 |
| Carland JE, Yamamoto I, Hanrahan JR, et al. (2015) A hydrophobic area of the GABA ρ₁ receptor containing phenylalanine 124 influences both receptor activation and deactivation. Journal of Molecular Neuroscience : Mn. 55: 305-13 |
| Moorhouse AJ, Lewis TM, Barry PH. (2015) Analyzing Ion Permeation in Channels and Pumps Using Patch-Clamp Recording Pumps, Channels and Transporters: Methods of Functional Analysis. 51-88 |
| Absalom NL, Quek G, Lewis TM, et al. (2013) Covalent trapping of methyllycaconitine at the α4-α4 interface of the α4β2 nicotinic acetylcholine receptor: antagonist binding site and mode of receptor inhibition revealed. The Journal of Biological Chemistry. 288: 26521-32 |
| Huang SH, Lewis TM, Lummis SC, et al. (2012) Mixed antagonistic effects of the ginkgolides at recombinant human Ï1 GABAC receptors. Neuropharmacology. 63: 1127-39 |
| Cederholm JM, Absalom NL, Sugiharto S, et al. (2010) Conformational changes in extracellular loop 2 associated with signal transduction in the glycine receptor. Journal of Neurochemistry. 115: 1245-55 |
| Sugiharto S, Carland JE, Lewis TM, et al. (2010) External divalent cations increase anion-cation permeability ratio in glycine receptor channels. Pflã¼Gers Archiv : European Journal of Physiology. 460: 131-52 |
| Barry PH, Sugiharto S, Lewis TM, et al. (2010) Further analysis of counterion permeation through anion-selective glycine receptor channels. Channels (Austin, Tex.). 4: 142-9 |
| Cederholm JM, Schofield PR, Lewis TM. (2009) Gating mechanisms in Cys-loop receptors. European Biophysics Journal : Ebj. 39: 37-49 |